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Clinical trial

An Open-label Randomized Phase 3 Study of Tucatinib in Combination With Trastuzumab and mFOLFOX6 Versus mFOLFOX6 Given With or Without Either Cetuximab or Bevacizumab as First-line Treatment for Subjects With HER2+ Metastatic Colorectal Cancer

NCT05253651 is registered in ClinicalTrials.gov with Seagen, a wholly owned subsidiary of Pfizer as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
An Open-label Randomized Phase 3 Study of Tucatinib in Combination With Trastuzumab and mFOLFOX6 Versus mFOLFOX6 Given With or Without Either Cetuximab or Bevacizumab as First-line Treatment for Subjects With HER2+ Metastatic Colorectal Cancer
Lead sponsor
Seagen, a wholly owned subsidiary of Pfizer
Phase
Phase 3
Overall status
Recruiting
Start date
October 24, 2022
Completion date
July 3, 2030
Enrollment
400 (estimated)
Sites
366

Conditions

As the registry lists them; a condition with its own page is linked.