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Clinical trial

Phase I Dose Escalation and Expansion Study of Tazemetostat in Combination With Topotecan and Pembrolizumab in Recurrent Small Cell Lung Cancer

NCT05353439 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Phase I Dose Escalation and Expansion Study of Tazemetostat in Combination With Topotecan and Pembrolizumab in Recurrent Small Cell Lung Cancer
Lead sponsor
National Cancer Institute (NCI)
Phase
Phase 1
Overall status
Active, not recruiting
Start date
July 27, 2022
Completion date
March 13, 2027
Enrollment
18 (actual)
Sites
15

Conditions

As the registry lists them; a condition with its own page is linked.

extensive stage lung small cell carcinoma, limited stage lung small cell carcinoma, platinum-resistant lung small cell carcinoma, platinum-sensitive lung small cell carcinoma, recurrent extensive stage lung small cell carcinoma, recurrent lung small cell carcinoma