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Clinical trial

A Phase 0 Clinical Trial to Evaluate Drug Concentrations and Pharmacodynamic Parameters of Niraparib in Tumor Tissue of Patients With Surgically Accessible Recurrent IDH 1/2 Gliomas

NCT05406700 is registered in ClinicalTrials.gov with Massachusetts General Hospital as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 0 Clinical Trial to Evaluate Drug Concentrations and Pharmacodynamic Parameters of Niraparib in Tumor Tissue of Patients With Surgically Accessible Recurrent IDH 1/2 Gliomas
Lead sponsor
Massachusetts General Hospital
Phase
Phase 1
Overall status
Active, not recruiting
Start date
May 18, 2023
Completion date
October 31, 2026
Enrollment
16 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

glioma, malignant, idh1 mutation, idh2 gene mutation, low-grade glioma, recurrent glioma