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Clinical trial

A Phase I Dose Escalation Study of Ascending Single and Multiple Doses of the MEK Inhibitor Zapnometinib in Healthy Subjects to Evaluate the Safety & Tolerability Compared to Placebo, Additionally Evaluating Pharmacokinetics and Pharmacodynamics of Target Engagement, as Well as Investigating Possible FDI and DDI

NCT05555823 is registered in ClinicalTrials.gov with Atriva Therapeutics GmbH as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase I Dose Escalation Study of Ascending Single and Multiple Doses of the MEK Inhibitor Zapnometinib in Healthy Subjects to Evaluate the Safety & Tolerability Compared to Placebo, Additionally Evaluating Pharmacokinetics and Pharmacodynamics of Target Engagement, as Well as Investigating Possible FDI and DDI
Lead sponsor
Atriva Therapeutics GmbH
Phase
Phase 1
Overall status
Completed
Start date
June 23, 2022
Completion date
July 20, 2023
Enrollment
96 (actual)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

healthy