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Clinical trial

A Phase 1/2 Study of CB-103 (Oral Pan-NOTCH Inhibitor) With Abemaciclib or Lenvatinib in Combination in Patients With NOTCH Activated Adenoid Cystic Carcinoma (CALCulus)

NCT05774899 is registered in ClinicalTrials.gov with Michael J. Dennis, MD as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1/2 Study of CB-103 (Oral Pan-NOTCH Inhibitor) With Abemaciclib or Lenvatinib in Combination in Patients With NOTCH Activated Adenoid Cystic Carcinoma (CALCulus)
Lead sponsor
Michael J. Dennis, MD
Phase
Phase 1/2
Overall status
Recruiting
Start date
June 1, 2023
Completion date
June 1, 2028
Enrollment
32 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

adenoid cystic carcinoma, metastatic adenoid cystic carcinoma, recurrent adenoid cystic carcinoma