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Clinical trial

An Open-label Study to Assess the Safety and Efficacy of Naporafenib (ERAS-254) Administered With Trametinib in Previously Treated Patients With Locally Advanced Unresectable or Metastatic Solid Tumor Malignancies With RAS Q61X Mutations

NCT05907304 is registered in ClinicalTrials.gov with Erasca, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
An Open-label Study to Assess the Safety and Efficacy of Naporafenib (ERAS-254) Administered With Trametinib in Previously Treated Patients With Locally Advanced Unresectable or Metastatic Solid Tumor Malignancies With RAS Q61X Mutations
Lead sponsor
Erasca, Inc.
Phase
Phase 1
Overall status
Active, not recruiting
Start date
August 17, 2023
Completion date
December 31, 2026
Enrollment
86 (actual)
Sites
29

Conditions

As the registry lists them; a condition with its own page is linked.

advanced or metastatic solid tumors