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Clinical trial

AN INTERVENTIONAL SAFETY AND EFFICACY PHASE 1B/2, OPEN-LABEL STUDY TO INVESTIGATE TOLERABILITY, PK, AND ANTITUMOR ACTIVITY OF VEPDEGESTRANT (ARV-471/PF-07850327), AN ORAL PROTEOLYSIS TARGETING CHIMERA, IN COMBINATION WITH PF-07220060 IN PARTICIPANTS AGED 18 YEARS AND OLDER WITH ER+/HER2- ADVANCED OR METASTATIC BREAST CANCER

NCT06206837 is registered in ClinicalTrials.gov with Pfizer as lead sponsor.

NCT NCT06206837
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Registry record

As filed in ClinicalTrials.gov.

Title
AN INTERVENTIONAL SAFETY AND EFFICACY PHASE 1B/2, OPEN-LABEL STUDY TO INVESTIGATE TOLERABILITY, PK, AND ANTITUMOR ACTIVITY OF VEPDEGESTRANT (ARV-471/PF-07850327), AN ORAL PROTEOLYSIS TARGETING CHIMERA, IN COMBINATION WITH PF-07220060 IN PARTICIPANTS AGED 18 YEARS AND OLDER WITH ER+/HER2- ADVANCED OR METASTATIC BREAST CANCER
Lead sponsor
Pfizer
Phase
Phase 1/2
Overall status
Active, not recruiting
Start date
February 19, 2024
Completion date
May 25, 2027
Enrollment
71 (actual)
Sites
58

Conditions

As the registry lists them; a condition with its own page is linked.

breast cancer