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Clinical trial

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

NCT06239272 is registered in ClinicalTrials.gov with St. Jude Children's Research Hospital as lead sponsor.

NCT NCT06239272
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Registry record

As filed in ClinicalTrials.gov.

Title
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)
Lead sponsor
St. Jude Children's Research Hospital
Phase
Phase 1/2
Overall status
Recruiting
Start date
March 27, 2024
Completion date
June 30, 2037
Enrollment
139 (estimated)
Sites
7

Conditions

As the registry lists them; a condition with its own page is linked.

adipocytic neoplasm, angiomatoid fibrous histiocytoma, angiosarcoma, atypical fibroxanthoma, clear cell sarcoma, dedifferentiated liposarcoma, dermatofibrosarcoma protuberans, fibrosarcomatous, epithelioid hemangioendothelioma, epithelioid sarcoma, extraskeletal myxoid chondrosarcoma, fibrosarcoma nos, giant cell tumor of soft parts nos, glomus tumor, granular cell tumor, malignant, inflammatory leiomyosarcoma, intimal sarcoma, leiomyosarcoma, liposarcoma, low grade fibromyxoid sarcoma, low grade myofibroblastic sarcoma, malignant peripheral nerve sheath tumor, malignant tenosynovial giant cell tumor of soft tissue, melanotic malignant nerve sheath tumor, myoepithelial carcinoma, myoepithelioma, myxofibrosarcoma, myxoid liposarcoma, myxoid pleomorphic liposarcoma, ntrk-rearranged spindle cell neoplasm, ossifying fibromyxoid tumor, malignant, osteosarcoma, extraskeletal, perineurioma, malignant, perivascular epithelioid tumor, malignant, phosphaturic mesenchymal tumor, malignant, pleomorphic liposarcoma, pleomorphic sarcoma, undifferentiated, round cell sarcoma, round cell sarcoma, undifferentiated, sclerosing epithelioid fibrosarcoma, synovial sarcoma, undifferentiated sarcoma, well differentiated liposarcoma