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Clinical trial

A Master Protocol for the Multi-Cohort, Open-Label, Phase 1/2 Study of DCC-3084 as Monotherapy and in Combination With Other Antitumor Agents in Participants With Advanced Malignancies Driven by the MAPK Pathway

NCT06287463 is registered in ClinicalTrials.gov with Deciphera Pharmaceuticals, LLC as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Master Protocol for the Multi-Cohort, Open-Label, Phase 1/2 Study of DCC-3084 as Monotherapy and in Combination With Other Antitumor Agents in Participants With Advanced Malignancies Driven by the MAPK Pathway
Lead sponsor
Deciphera Pharmaceuticals, LLC
Phase
Phase 1
Overall status
Terminated
Start date
May 14, 2024
Completion date
February 13, 2026
Enrollment
29 (actual)
Sites
9

Conditions

As the registry lists them; a condition with its own page is linked.

advanced solid tumor, braf gene mutation, castration-resistant prostate cancer (crpc), craf gene mutation, melanoma, nf1 mutation, non-small cell lung cancer, pancreatic ductal adenocarcinoma, raf mutation, ras mutation