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Clinical trial

Multicentre Phase I/IIa Study of Infusion of Autologous Peripheral Blood T Lymphocytes Expanded and Genetically Modified Using Sleeping Beauty Family Transposons to Express a Chimeric Antigenic Receptor With Anti-CD19 Specificity Conjugated to the 4-1BB Co-stimulatory Region and CD3z and huEGFRt Signal Transmission (TranspoCART19) in Patients With Relapsed or Refractory B-cell Lymphoma

NCT06378190 is registered in ClinicalTrials.gov with Instituto de Investigación Biomédica de Salamanca as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Multicentre Phase I/IIa Study of Infusion of Autologous Peripheral Blood T Lymphocytes Expanded and Genetically Modified Using Sleeping Beauty Family Transposons to Express a Chimeric Antigenic Receptor With Anti-CD19 Specificity Conjugated to the 4-1BB Co-stimulatory Region and CD3z and huEGFRt Signal Transmission (TranspoCART19) in Patients With Relapsed or Refractory B-cell Lymphoma
Lead sponsor
Instituto de Investigación Biomédica de Salamanca
Phase
Phase 1/2
Overall status
Recruiting
Start date
March 11, 2024
Completion date
July 31, 2030
Enrollment
27 (estimated)
Sites
8

Conditions

As the registry lists them; a condition with its own page is linked.

b-cell lymphoma recurrent, refractory b-cell lymphoma