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Clinical trial

A Phase 1 Prospective, Open-label, First-in-human Study to Evaluate the Safety, Tolerability and Biodistribution of [177Lu]Lu-AKIR001 and Its Anti-tumour Effect in Adult Patients With CD44v6 Expressing Solid Tumours

NCT06639191 is registered in ClinicalTrials.gov with Karolinska University Hospital as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1 Prospective, Open-label, First-in-human Study to Evaluate the Safety, Tolerability and Biodistribution of [177Lu]Lu-AKIR001 and Its Anti-tumour Effect in Adult Patients With CD44v6 Expressing Solid Tumours
Lead sponsor
Karolinska University Hospital
Phase
Phase 1
Overall status
Recruiting
Start date
January 28, 2026
Completion date
November 1, 2028
Enrollment
15 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

cancer head and neck, cervix carcinoma, non-small cell lung cancer stage iv, poorly differentiated thyroid carcinoma, thyroid gland anaplastic carcinoma, vulvar cancer, stage iv