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Clinical trial

Safety and Efficacy of Anti-CD123 Chimeric Antigen Receptor-Modified Autologous T Cells (CART123) in Patients With Relapsed/Refractory CD123+ Hematologic Malignancies: A Dose Escalation, Open-Label, Phase I Study

NCT06765876 is registered in ClinicalTrials.gov with Institute of Hematology and Blood Transfusion, Czech Republic as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Safety and Efficacy of Anti-CD123 Chimeric Antigen Receptor-Modified Autologous T Cells (CART123) in Patients With Relapsed/Refractory CD123+ Hematologic Malignancies: A Dose Escalation, Open-Label, Phase I Study
Lead sponsor
Institute of Hematology and Blood Transfusion, Czech Republic
Phase
Phase 1
Overall status
Active, not recruiting
Start date
October 23, 2024
Completion date
December 31, 2028
Enrollment
18 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

blastic plasmacytoid dendritic cell neoplasm (bpdcn), leukemia, myeloid, acute(aml), myelodysplastic syndromes (mds), precursor cell lymphoblastic leukemia-lymphoma