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Clinical trial

A Phase 1/2 Study of a Selective FGFR2/3 Inhibitor, CGT4859, in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors Harboring FGFR2 and/or FGFR3 Genetic Alterations

NCT06777316 is registered in ClinicalTrials.gov with Cogent Biosciences, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1/2 Study of a Selective FGFR2/3 Inhibitor, CGT4859, in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors Harboring FGFR2 and/or FGFR3 Genetic Alterations
Lead sponsor
Cogent Biosciences, Inc.
Phase
Phase 1/2
Overall status
Active, not recruiting
Start date
January 22, 2025
Completion date
June 30, 2027
Enrollment
110 (estimated)
Sites
13

Conditions

As the registry lists them; a condition with its own page is linked.

advanced solid tumors, cholangiocarcinoma, fgfr2 gene amplification, fgfr2 gene fusion/rearrangement, fgfr2 gene short variants, fgfr2 genetic alterations, fgfr3 gene amplification, fgfr3 gene fusion/rearrangement, fgfr3 gene short variants, fgfr3 genetic alterations, intrahepatic cholangiocarcinoma (icc), other solid tumors, adult