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Clinical trial

A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of AZD1390 (NSC# 852149) When Combined With Focal Radiation in Pediatric Patients With High Grade Glioma

NCT06894979 is registered in ClinicalTrials.gov with Children's Oncology Group as lead sponsor.

NCT NCT06894979
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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of AZD1390 (NSC# 852149) When Combined With Focal Radiation in Pediatric Patients With High Grade Glioma
Lead sponsor
Children's Oncology Group
Phase
Phase 1
Overall status
Active, not recruiting
Start date
June 18, 2025
Completion date
March 31, 2028
Enrollment
54 (estimated)
Sites
22

Conditions

As the registry lists them; a condition with its own page is linked.

childhood astrocytoma, childhood diffuse intrinsic pontine glioma, childhood diffuse midline glioma, childhood glioblastoma, childhood malignant glioma