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Clinical trial

A Phase I/Ib Trial of Idetrexed (Alpha Folate Receptor Targeted Thymidylate Synthase Inhibitor) in Combination With Olaparib (a PARP Inhibitor) at Different Doses in Patients With Ovarian Cancer (IDOL)

NCT06976892 is registered in ClinicalTrials.gov with Institute of Cancer Research, United Kingdom as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase I/Ib Trial of Idetrexed (Alpha Folate Receptor Targeted Thymidylate Synthase Inhibitor) in Combination With Olaparib (a PARP Inhibitor) at Different Doses in Patients With Ovarian Cancer (IDOL)
Lead sponsor
Institute of Cancer Research, United Kingdom
Phase
Phase 1
Overall status
Recruiting
Start date
August 31, 2025
Completion date
December 31, 2029
Enrollment
33 (estimated)
Sites
3

Conditions

As the registry lists them; a condition with its own page is linked.

high grade serous ovarian cancer