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Clinical trial

NECTINIUM-2: A Phase 1b, 2 Part, Multicenter, Single Arm, Open Label Study to Evaluate the Safety and Efficacy of a Nectin-4 Radiopharmaceutical ([225Ac]Ac-AKY-1189) in Patients With Previously Treated Locally Advanced or Metastatic Solid Tumors

NCT07020117 is registered in ClinicalTrials.gov with Aktis Oncology, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
NECTINIUM-2: A Phase 1b, 2 Part, Multicenter, Single Arm, Open Label Study to Evaluate the Safety and Efficacy of a Nectin-4 Radiopharmaceutical ([225Ac]Ac-AKY-1189) in Patients With Previously Treated Locally Advanced or Metastatic Solid Tumors
Lead sponsor
Aktis Oncology, Inc.
Phase
Phase 1
Overall status
Recruiting
Start date
August 22, 2025
Completion date
June 30, 2032
Enrollment
150 (estimated)
Sites
14

Conditions

As the registry lists them; a condition with its own page is linked.

cervical adenocarcinoma, colorectal adenocarcinoma, head and neck cancer, hormone receptor positive breast adenocarcinoma, non small cell lung cancer, triple negative breast cancer (tnbc), urothelial carcinoma bladder