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Clinical trial

A Randomized, Double-blind, Sponsor-open, Placebo-controlled Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single and Multiple Ascending Doses of ORX142 in Healthy Adults, Single Doses of ORX142 in Healthy Older Adults, and a Single Dose Crossover, Proof-of-concept Study of ORX142 in Acutely Sleep-deprived Healthy Subjects

NCT07082829 is registered in ClinicalTrials.gov with Centessa Pharmaceuticals (UK) Limited as lead sponsor.

NCT NCT07082829
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Registry record

As filed in ClinicalTrials.gov.

Title
A Randomized, Double-blind, Sponsor-open, Placebo-controlled Study of the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Food Effect of Single and Multiple Ascending Doses of ORX142 in Healthy Adults, Single Doses of ORX142 in Healthy Older Adults, and a Single Dose Crossover, Proof-of-concept Study of ORX142 in Acutely Sleep-deprived Healthy Subjects
Lead sponsor
Centessa Pharmaceuticals (UK) Limited
Phase
Phase 1
Overall status
Recruiting
Start date
June 30, 2025
Completion date
June 15, 2026
Enrollment
208 (estimated)
Sites
3

Conditions

As the registry lists them; a condition with its own page is linked.

excessive daytime sleepiness