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Clinical trial

BAF_FRontier-1, A First-in-Human, Phase 1 Trial to Assess Safety, Tolerability, and Preliminary Efficacy of LY4152199, a B-cell Activation Factor Receptor (BAFF-R) T-Cell Engager Bispecific Antibody in Adult Participants With Previously Treated B-cell Malignancies

NCT07101328 is registered in ClinicalTrials.gov with Eli Lilly and Company as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
BAF_FRontier-1, A First-in-Human, Phase 1 Trial to Assess Safety, Tolerability, and Preliminary Efficacy of LY4152199, a B-cell Activation Factor Receptor (BAFF-R) T-Cell Engager Bispecific Antibody in Adult Participants With Previously Treated B-cell Malignancies
Lead sponsor
Eli Lilly and Company
Phase
Phase 1
Overall status
Recruiting
Start date
May 28, 2026
Completion date
September 30, 2029
Enrollment
215 (estimated)
Sites
51

Conditions

As the registry lists them; a condition with its own page is linked.

b-cell lymphoma, lymphoma, b-cell marginal zone, lymphoma, follicular, lymphoma, large b-cell, diffuse, lymphoma, mantle cell, lymphoma, non-hodgkin, waldenstrom macroglobulinemia