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Clinical trial

Phase 1/2 Master Protocol for Open-Label, Multi-Centre, Single-Arm Sub-Studies, First in Human Clinical Studies of TCR-T Therapy (Autologous TCR- Modified T-Cell Therapy) Targeting Mutated Kirsten Rat Sarcoma (mutKRAS) Administered in Metastatic or Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC) Adult Patients With Specific mutKRAS and Human Leukocyte Antigen (HLA) Genotypes

NCT07145450 is registered in ClinicalTrials.gov with Anocca AB as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Phase 1/2 Master Protocol for Open-Label, Multi-Centre, Single-Arm Sub-Studies, First in Human Clinical Studies of TCR-T Therapy (Autologous TCR- Modified T-Cell Therapy) Targeting Mutated Kirsten Rat Sarcoma (mutKRAS) Administered in Metastatic or Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC) Adult Patients With Specific mutKRAS and Human Leukocyte Antigen (HLA) Genotypes
Lead sponsor
Anocca AB
Phase
Phase 1/2
Overall status
Recruiting
Start date
July 3, 2025
Completion date
July 31, 2030
Enrollment
96 (estimated)
Sites
10

Conditions

As the registry lists them; a condition with its own page is linked.

pdac