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Clinical trial

A Multicenter, Randomized, Double-Blind, Exploratory Clinical Trial to Evaluate the Efficacy and Safety in Concomitant Administration of Macitentan and Dapagliflozin in Patients With Heart Failure With Mildly Reduced and Preserved Ejection Fraction (HFmrEF and HFpEF) and Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH)

NCT07147114 is registered in ClinicalTrials.gov with Gachon University Gil Medical Center as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Multicenter, Randomized, Double-Blind, Exploratory Clinical Trial to Evaluate the Efficacy and Safety in Concomitant Administration of Macitentan and Dapagliflozin in Patients With Heart Failure With Mildly Reduced and Preserved Ejection Fraction (HFmrEF and HFpEF) and Combined Pre- and Post-capillary Pulmonary Hypertension (CpcPH)
Lead sponsor
Gachon University Gil Medical Center
Phase
Phase 4
Overall status
Recruiting
Start date
November 24, 2025
Completion date
September 30, 2027
Enrollment
64 (estimated)
Sites
15

Conditions

As the registry lists them; a condition with its own page is linked.

combined pre- and post-capillary pulmonary hypertension, cpcph, group 2 pulmonary hypertension, hfmref, hfpef