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Clinical trial

Phase 1 First-in-Human, Dose Escalation and Dose Expansion Study of RYZ401, a Novel Radiopharmaceutical Therapy Labeled With Actinium-225, in Subjects With Neuroendocrine Tumors and Other Solid Tumors Expressing Somatostatin Receptors.

NCT07165132 is registered in ClinicalTrials.gov with RayzeBio, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Phase 1 First-in-Human, Dose Escalation and Dose Expansion Study of RYZ401, a Novel Radiopharmaceutical Therapy Labeled With Actinium-225, in Subjects With Neuroendocrine Tumors and Other Solid Tumors Expressing Somatostatin Receptors.
Lead sponsor
RayzeBio, Inc.
Phase
Phase 1
Overall status
Recruiting
Start date
December 3, 2025
Completion date
April 30, 2033
Enrollment
104 (estimated)
Sites
14

Conditions

As the registry lists them; a condition with its own page is linked.

carcinoid, carcinoid tumor, gastroenteropancreatic neuroendocrine tumor, gastroenteropancreatic neuroendocrine tumor disease, gep-net, neuroendocrine tumors, pancreatic net, solid tumor, somatostatin receptor