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Clinical trial

RETAIN: A Phase 2/3 Randomized, Placebo-Controlled Study to Evaluate the Efficacy of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Total Knee Arthroplasty (TKA)

NCT07214311 is registered in ClinicalTrials.gov with Peptilogics as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
RETAIN: A Phase 2/3 Randomized, Placebo-Controlled Study to Evaluate the Efficacy of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Total Knee Arthroplasty (TKA)
Lead sponsor
Peptilogics
Phase
Phase 2/3
Overall status
Recruiting
Start date
February 3, 2026
Completion date
September 30, 2028
Enrollment
240 (estimated)
Sites
19

Conditions

As the registry lists them; a condition with its own page is linked.

prosthetic-joint infection