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Clinical trial

A Phase Ⅰ/Ⅱa Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HMPL-A251 in Participants With Advanced or Metastatic HER2-Expressing Solid Tumors

NCT07228247 is registered in ClinicalTrials.gov with Hutchmed as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase Ⅰ/Ⅱa Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of HMPL-A251 in Participants With Advanced or Metastatic HER2-Expressing Solid Tumors
Lead sponsor
Hutchmed
Phase
Phase 1/2
Overall status
Recruiting
Start date
December 16, 2025
Completion date
December 31, 2028
Enrollment
147 (estimated)
Sites
15

Conditions

As the registry lists them; a condition with its own page is linked.

solid tumors, adult