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Clinical trial

A Phase II Multi-institutional Randomized Trial Evaluating the Impact of GLP-1 Receptor Agonists in Combination With Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer

NCT07314528 is registered in ClinicalTrials.gov with St. James's Hospital, Ireland as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase II Multi-institutional Randomized Trial Evaluating the Impact of GLP-1 Receptor Agonists in Combination With Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer
Lead sponsor
St. James's Hospital, Ireland
Phase
Phase 2
Overall status
Not yet recruiting
Start date
April 30, 2026
Completion date
September 30, 2028
Enrollment
42 (estimated)
Sites
Not reported

Conditions

As the registry lists them; a condition with its own page is linked.

glp-1, locally advanced rectal cancer (larc), obesity & overweight, rectal cancer patients, total neoadjuvant therapy