Clinical trial
A Phase 1, Open Label, Dose-Escalation and Expansion Study to Evaluate Safety, Pharmacokinetics and Initial Therapeutic Activity of AVA6103, a Novel FAP-activated Exatecan Administered Intravenously in Subjects With Locally Advanced or Metastatic Selected Solid Tumors
NCT07454642 is registered in ClinicalTrials.gov with Avacta Life Sciences Ltd as lead sponsor.
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Registry record
As filed in ClinicalTrials.gov.
- Title
- A Phase 1, Open Label, Dose-Escalation and Expansion Study to Evaluate Safety, Pharmacokinetics and Initial Therapeutic Activity of AVA6103, a Novel FAP-activated Exatecan Administered Intravenously in Subjects With Locally Advanced or Metastatic Selected Solid Tumors
- Lead sponsor
- Avacta Life Sciences Ltd
- Phase
- Phase 1
- Overall status
- Recruiting
- Start date
- March 31, 2026
- Completion date
- June 30, 2030
- Enrollment
- 174 (estimated)
- Sites
- 7
Conditions
As the registry lists them; a condition with its own page is linked.
cervical adenocarcinoma, cervical adenosquamous carcinoma, colorectal cancer, gastric adenocarcinoma, gej adenocarcinoma, hormone receptor positive breast carcinoma, pdac - pancreatic ductal adenocarcinoma, small cell carcinoma of lung, vulvar adenocarcinoma