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Clinical trial

A First-in-Human Phase 1/2, Dose Escalation and Dose Expansion Study to Evaluate Safety, Tolerability, and Preliminary Efficacy of Claudin18.2 (CLDN18.2)-Directed Antibody-Drug Conjugate (ADC) LCB02A in Patients With CLDN18.2-positive Advanced Solid Tumors

NCT07460375 is registered in ClinicalTrials.gov with LigaChem Biosciences, Inc. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A First-in-Human Phase 1/2, Dose Escalation and Dose Expansion Study to Evaluate Safety, Tolerability, and Preliminary Efficacy of Claudin18.2 (CLDN18.2)-Directed Antibody-Drug Conjugate (ADC) LCB02A in Patients With CLDN18.2-positive Advanced Solid Tumors
Lead sponsor
LigaChem Biosciences, Inc.
Phase
Phase 1/2
Overall status
Recruiting
Start date
August 31, 2026
Completion date
August 31, 2030
Enrollment
191 (estimated)
Sites
8

Conditions

As the registry lists them; a condition with its own page is linked.

advanced solid tumors