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Clinical trial

A Proof-of-Concept, Multicentre, Phase IIb, Randomized Double-Blind Crossover Trial of Levetiracetam vs Placebo for Hippocampal Hyperactivity in Cognitively Normal Individuals at Risk for Alzheimer's Disease

NCT07477431 is registered in ClinicalTrials.gov with Sunnybrook Health Sciences Centre as lead sponsor.

NCT NCT07477431
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Registry record

As filed in ClinicalTrials.gov.

Title
A Proof-of-Concept, Multicentre, Phase IIb, Randomized Double-Blind Crossover Trial of Levetiracetam vs Placebo for Hippocampal Hyperactivity in Cognitively Normal Individuals at Risk for Alzheimer's Disease
Lead sponsor
Sunnybrook Health Sciences Centre
Phase
Phase 2
Overall status
Recruiting
Start date
October 23, 2025
Completion date
February 29, 2028
Enrollment
40 (estimated)
Sites
2

Conditions

As the registry lists them; a condition with its own page is linked.

hippocampal hyperactivation, prodromal alzheimer disease