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Clinical trial

A Phase I Study to Assess the Safety and Antitumor Activity of Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease

NCT07509034 is registered in ClinicalTrials.gov with National Cancer Institute (NCI) as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase I Study to Assess the Safety and Antitumor Activity of Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory Disease
Lead sponsor
National Cancer Institute (NCI)
Phase
Phase 1
Overall status
Recruiting
Start date
October 19, 2026
Completion date
January 30, 2031
Enrollment
40 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

extensive-stage small cell lung cancer, extrapulmonary small cell carcinoma, high-grade neuroendocrine carcinoma, neuroendocrine carcinoma, poorly differentiated neuroendocrine carcinoma, recurrent small cell lung cancer, refractory small cell lung cancer, small cell lung cancer, small cell lung carcinoma