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Clinical trial

AN INTERVENTIONAL PHASE 3, OPEN LABEL, RANDOMIZED STUDY TO EVALUATE EFFICACY AND SAFETY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY VERSUS PEMBROLIZUMAB IN COMBINATION WITH CHEMOTHERAPY IN ADULT PARTICIPANTS WITH ADVANCED OR RECURRENT MISMATCH REPAIR PROFICIENT ENDOMETRIAL CANCER

NCT07578649 is registered in ClinicalTrials.gov with Pfizer as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
AN INTERVENTIONAL PHASE 3, OPEN LABEL, RANDOMIZED STUDY TO EVALUATE EFFICACY AND SAFETY OF PF-08634404 IN COMBINATION WITH CHEMOTHERAPY VERSUS PEMBROLIZUMAB IN COMBINATION WITH CHEMOTHERAPY IN ADULT PARTICIPANTS WITH ADVANCED OR RECURRENT MISMATCH REPAIR PROFICIENT ENDOMETRIAL CANCER
Lead sponsor
Pfizer
Phase
Phase 3
Overall status
Not yet recruiting
Start date
October 9, 2026
Completion date
January 30, 2031
Enrollment
600 (estimated)
Sites
43

Conditions

As the registry lists them; a condition with its own page is linked.

endometrial cancer, endometrial neoplasms