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Clinical trial

Impact of Genetic Variants on the Toxicity of Antibody-Drug Conjugates in Locally Advanced or Metastatic Breast Cancer: The Role of the UGT1A1 Gene as a Predictive Biomarker of Therapeutic Response

NCT07582887 is registered in ClinicalTrials.gov with Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Impact of Genetic Variants on the Toxicity of Antibody-Drug Conjugates in Locally Advanced or Metastatic Breast Cancer: The Role of the UGT1A1 Gene as a Predictive Biomarker of Therapeutic Response
Lead sponsor
Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
Phase
Observational
Overall status
Recruiting
Start date
July 15, 2025
Completion date
March 31, 2027
Enrollment
70 (estimated)
Sites
1

Conditions

As the registry lists them; a condition with its own page is linked.

breast cancer, drug-related side effects and adverse reactions, metastatic breast cancer, pharmacogenetic variant