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Clinical trial

A Phase 1/2, First-in-Human, Open-Label, Multicenter, Single-Dose Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of NVC-001, a Novel Adeno-Associated Virus (Serotype 9) Vector Expressing a Dominant Negative SUN1 Transgene, in Patients With LMNA-Related Dilated Cardiomyopathy (SUNBEAM-LMNA)

NCT07606274 is registered in ClinicalTrials.gov with Nuevocor Pte. Ltd. as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 1/2, First-in-Human, Open-Label, Multicenter, Single-Dose Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of NVC-001, a Novel Adeno-Associated Virus (Serotype 9) Vector Expressing a Dominant Negative SUN1 Transgene, in Patients With LMNA-Related Dilated Cardiomyopathy (SUNBEAM-LMNA)
Lead sponsor
Nuevocor Pte. Ltd.
Phase
Phase 1/2
Overall status
Recruiting
Start date
June 16, 2026
Completion date
March 31, 2030
Enrollment
21 (estimated)
Sites
8

Conditions

As the registry lists them; a condition with its own page is linked.

lmna-related dilated cardiomyopathy