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Clinical trial

Post-Authorisation Safety Study: A Cohort Event Monitoring Study to Characterise the Use of Eplontersen in Patients With Prior Liver Transplant and Pre-existing Severe Hepatic Impairment and to Assess Long-term Safety Among All New Users of Eplontersen (sTTRing)

NCT07654855 is registered in ClinicalTrials.gov with AstraZeneca as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
Post-Authorisation Safety Study: A Cohort Event Monitoring Study to Characterise the Use of Eplontersen in Patients With Prior Liver Transplant and Pre-existing Severe Hepatic Impairment and to Assess Long-term Safety Among All New Users of Eplontersen (sTTRing)
Lead sponsor
AstraZeneca
Phase
Observational
Overall status
Recruiting
Start date
September 1, 2026
Completion date
January 29, 2032
Enrollment
320 (estimated)
Sites
6

Conditions

As the registry lists them; a condition with its own page is linked.

transthyretin amyloidosis, transthyretin amyloidosis with cardiomyopathy, transthyretin amyloidosis with polyneuropathy