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Clinical trial

A Phase 3, Randomized, Double-Masked, Active-Controlled Trial to Evaluate the Efficacy, Safety, and Durability of a Single Intravitreal Injection of 4D-150 Versus Aflibercept in Adults With Diabetic Macular Edema (4SIGHT)

NCT07867080 is registered in ClinicalTrials.gov with 4D Molecular Therapeutics as lead sponsor.

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Registry record

As filed in ClinicalTrials.gov.

Title
A Phase 3, Randomized, Double-Masked, Active-Controlled Trial to Evaluate the Efficacy, Safety, and Durability of a Single Intravitreal Injection of 4D-150 Versus Aflibercept in Adults With Diabetic Macular Edema (4SIGHT)
Lead sponsor
4D Molecular Therapeutics
Phase
Phase 3
Overall status
Recruiting
Start date
September 18, 2026
Completion date
January 31, 2030
Enrollment
514 (estimated)
Sites
82

Conditions

As the registry lists them; a condition with its own page is linked.

diabetic macular edema (dme)