Condition (MeSH)
Bunion
ClinicalTrials.gov lists 58 trials for Bunion or a narrower condition beneath it. Pacira Pharmaceuticals, Inc has the most among industry and government lead sponsors, with 5.
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Trials per phase
58 of the 58 trials are tagged with Bunion itself; the rest are tagged with a narrower condition beneath it.
When did Bunion trials start? (20)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 8
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 1 |
| 2024 | 5 |
| 2023 | 3 |
| 2022 | 2 |
| 2021 | 4 |
| 2020 | 5 |
| 2019 | 2 |
| 2018 | 8 |
| 2017 | 6 |
Showing 10 of 20 earlier years.
No forecast is made for this condition: it averages 2.4 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Bunion trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 1/2 | 1 |
| Phase 2 | 12 |
| Phase 2/3 | 1 |
| Phase 3 | 15 |
| Phase 4 | 2 |
| Not applicable | 15 |
| Observational | 10 |
How many Bunion trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 3 |
| Recruiting | 1 |
| Active, not recruiting | 3 |
| Completed | 38 |
| Terminated | 6 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Bunion trials? (11)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Pacira Pharmaceuticals, Inc | 5 |
| Baudax Bio | 4 |
| Heron Therapeutics | 4 |
| Cali Pharmaceuticals LLC | 3 |
| Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 2 |
Showing 5 of 11 sponsors.
Which drugs are being tested for Bunion? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| +/- Bupivacaine HCl | 10 |
| Oxycodone | 2 |
| Meloxicam | 2 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Intranasal Dexmedetomidine | 2 |
| Ropivacaine 2 % | 2 |
| Tapentadol (CG5503) ER | 2 |
| HTX-011 | 2 |
| HTX-009 | 1 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Bunion trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Atrial septal defect | 2 | 1 |
| Deep vein thrombosis | 2 | 2 |
| Deep vein thrombosis postoperative | 2 | 1 |
| Impaired healing | 2 | 1 |
| Allergic reaction | 1 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Bunion? (5)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Efficacy, safety, and pharmacokinetics of CPL-01, an investigational long-acting ropivacaine, in bunionectomy: Results of a phase 2b study. | The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons | 2025 | Yes |
| First Metatarsal Rotation in Hallux Valgus Deformity. | Foot & ankle international | 2021 | Yes |
| Comparison of Minimally Invasive and Traditionally Open Surgeries in Correction of Hallux Valgus: A Meta-Analysis. | The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons | 2020 | Yes |
| Efficacy and Safety of an Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination After Bunionectomy: a Randomized, Double-blind, Factorial, Placebo-controlled Trial. | Clinical therapeutics | 2019 | Yes |
| Sciatic neuropathy due to popliteal fossa nerve block. | Muscle & nerve | 2017 | No |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.