Condition (MeSH)
Breast Cancer Lymphedema
ClinicalTrials.gov lists 122 trials for Breast Cancer Lymphedema or a narrower condition beneath it. Koya Medical, Inc. has the most among industry and government lead sponsors, with 3.
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Trials per phase (log scale)
122 of the 122 trials are tagged with Breast Cancer Lymphedema itself; the rest are tagged with a narrower condition beneath it.
When did Breast Cancer Lymphedema trials start? (16)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 16
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 10 |
| 2025 | 16 |
| 2024 | 12 |
| 2023 | 10 |
| 2022 | 11 |
| 2021 | 15 |
| 2020 | 10 |
| 2019 | 11 |
| 2018 | 7 |
| 2017 | 4 |
Showing 10 of 16 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 14 trials starting in 2026 and about 15 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 36 months from start to primary completion across 23 trials still running at the 2026-10-09 snapshot; registered median of 13 months across 58 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Breast Cancer Lymphedema trials in? (7)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 1/2 | 1 |
| Phase 2 | 3 |
| Phase 3 | 2 |
| Phase 4 | 1 |
| Not applicable | 91 |
| Observational | 23 |
How many Breast Cancer Lymphedema trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 13 |
| Recruiting | 17 |
| Enrolling by invitation | 1 |
| Active, not recruiting | 9 |
| Completed | 55 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Breast Cancer Lymphedema trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Koya Medical, Inc. | 3 |
| Instituto Nacional de Cancer, Brazil | 2 |
Interventions as named in the registry (10)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Exercise | 3 |
| Indocyanine Green dye | 2 |
| Acupuncture | 1 |
| Lymfactin® [1 x 10E11 vp] | 1 |
| Protopic 0.1 % Topical Ointment | 1 |
Showing 5 of 10 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Breast Cancer Lymphedema trials report? (1)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Acute pyelonephritis | 1 | 1 |
Which publications cover Breast Cancer Lymphedema? (98)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Outcomes of Lymphovenous Anastomoses and Vascularized Lymph Node Transplant in the Combined Surgical Treatment of Lymphedema: A Prospective Cohort Study. | Plastic and reconstructive surgery | 2026 | Yes |
| Axillary Surgery in Breast Cancer - Primary Results of the INSEMA Trial. | The New England journal of medicine | 2025 | Yes |
| Advancing women's health with a pioneering implant to treat breast cancer related lymphedema. | European journal of internal medicine | 2025 | Yes |
| The LYMPH trial: comparing microsurgical with conservative treatment for chronic breast cancer-associated lymphoedema - study protocol of a pragmatic randomised international multicentre superiority trial. | BMJ open | 2025 | Yes |
| Randomized Trial Assessing Prospective Surveillance and Exercise for Preventing Breast Cancer-Related Lymphedema in High-Risk Patients. | Archives of physical medicine and rehabilitation | 2025 | Yes |
Showing 5 of 98 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.