Condition (MeSH)
Procedural Pain
ClinicalTrials.gov lists 112 trials for Procedural Pain or a narrower condition beneath it. Hamad Medical Corporation has the most among industry and government lead sponsors, with 2.
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Trials per phase (log scale)
112 of the 112 trials are tagged with Procedural Pain itself; the rest are tagged with a narrower condition beneath it.
When did Procedural Pain trials start? (18)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 2 trials are registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 16
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 21 |
| 2025 | 16 |
| 2024 | 15 |
| 2023 | 8 |
| 2022 | 8 |
| 2021 | 10 |
| 2020 | 6 |
| 2019 | 9 |
| 2018 | 4 |
| 2017 | 5 |
Showing 10 of 18 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 24 trials starting in 2026 and about 19 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 21 months from start to primary completion across 12 trials still running at the 2026-10-09 snapshot; registered median of 6 months across 68 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Procedural Pain trials in? (6)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 1 |
| Phase 2/3 | 2 |
| Phase 3 | 6 |
| Phase 4 | 7 |
| Not applicable | 92 |
| Observational | 4 |
How many Procedural Pain trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 12 |
| Recruiting | 12 |
| Enrolling by invitation | 3 |
| Active, not recruiting | 3 |
| Completed | 66 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Procedural Pain trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Hamad Medical Corporation | 2 |
Which drugs are being tested for Procedural Pain? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| PMI-150 (intranasal ketamine) | 2 |
| FENTANYL | 2 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Standard Care | 3 |
| Shotblocker | 3 |
| Control (placebo) group | 2 |
| L:Lidocaine | 2 |
| Double distilled water | 1 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Procedural Pain? (258)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| A Randomized Controlled Trial of Commercially Available Virtual Reality for Intravenous Cannulation-Related Distress in Children. | The Journal of pediatrics | 2026 | Yes |
| Methoxyflurane analgesia for outpatient hysteroscopy: A double-blind, randomised, controlled trial. | The Australian & New Zealand journal of obstetrics & gynaecology | 2025 | Yes |
| Prospective randomized controlled trial of water exchange plus cap versus water exchange colonoscopy in unsedated veterans. | Gastrointestinal endoscopy | 2025 | Yes |
| Standard of care versus standard of care plus Ericksonian hypnosis for percutaneous liver biopsy: Results of a randomized control trial. | Diagnostic and interventional imaging | 2025 | Yes |
| Pharmacological and non-pharmacological interventions for pain control in outpatient hysteroscopy: A systematic review. | European journal of obstetrics, gynecology, and reproductive biology | 2025 | Yes |
Showing 5 of 258 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.