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Condition (MeSH)

Molar Hypomineralization

ClinicalTrials.gov lists 129 trials for Molar Hypomineralization or a narrower condition beneath it.

MeSH D000094604 Stomatognathic Diseases C07 C16
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Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 1 Phase 4 Phase 4 2 Not applicable Not applicable 87 Observational Observational 29 Phase 1 Phase 1 3 Phase 1/2 Phase 1/2 5 Phase 2 Phase 2 1 Phase 2/3 Phase 2/3 1 Phase 3 Phase 3 1 Phase 4 Phase 4 2 Not applicable Not applicable 87 Observational Observational 29

Trials per phase (log scale)

129 of the 129 trials are tagged with Molar Hypomineralization itself; the rest are tagged with a narrower condition beneath it.

Get the Molar Hypomineralization report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Molar Hypomineralization trials start? (14)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 22

2012: 1 trials (Not applicable 1) 2013: 1 trials (Not applicable 1) 2014: 1 trials (Not applicable 1) 2015: 1 trials (Not applicable 1) 2017: 1 trials (Not applicable 1) 2018: 9 trials (Observational 4, Not applicable 4, Phase 1 1) 2019: 5 trials (Observational 1, Not applicable 3, Phase 1 1) 2020: 11 trials (Observational 4, Not applicable 7) 2021: 12 trials (Observational 3, Not applicable 8, Phase 1/2 1) 2022: 11 trials (Observational 3, Not applicable 5, Phase 1/2 3) 2023: 15 trials (Observational 3, Not applicable 10, Phase 4 1, Phase 1/2 1) 2024: 21 trials (Observational 4, Not applicable 14, Phase 4 1, Phase 2/3 1, Phase 1 1) 2025: 22 trials (Observational 3, Not applicable 17, Phase 3 1, Phase 2 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 17
2025 22
2024 21
2023 15
2022 11
2021 12
2020 11
2019 5
2018 9
2017 1

Forecast of the full-year count, planned starts included, not rows of this table: about 21 trials starting in 2026 and about 20 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 32 months from start to primary completion across 7 trials still running at the 2026-10-09 snapshot; registered median of 12 months across 60 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Molar Hypomineralization trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 3
Phase 1/2 5
Phase 2 1
Phase 2/3 1
Phase 3 1
Phase 4 2
Not applicable 87
Observational 29

How many Molar Hypomineralization trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 20
Recruiting 9
Enrolling by invitation 3
Active, not recruiting 7
Completed 59

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Resin infiltration 6
Silver diamine Fluoride 38% 3
fluoridated toothpaste (Colgate Total PROTECTION ACTIVE) 3
Fluoride Varnish 3
ART 2

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Molar Hypomineralization? (14)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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