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Condition (MeSH)

Stomatognathic Diseases

ClinicalTrials.gov lists 12,640 trials for Stomatognathic Diseases or a narrower condition beneath it. National Cancer Institute (NCI) has the most among industry and government lead sponsors, with 104.

MeSH D009057 Stomatognathic Diseases C07
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Phase 1 Phase 1 582 Phase 1/2 Phase 1/2 278 Phase 2 Phase 2 1,200 Phase 2/3 Phase 2/3 197 Phase 3 Phase 3 727 Phase 4 Phase 4 626 Not applicable Not applicable 6,449 Observational Observational 2,574 Phase 1 Phase 1 582 Phase 1/2 Phase 1/2 278 Phase 2 Phase 2 1,200 Phase 2/3 Phase 2/3 197 Phase 3 Phase 3 727 Phase 4 Phase 4 626 Not applicable Not applicable 6,449 Observational Observational 2,574

Trials per phase (log scale)

2 more sections with rows

80 of the 12,640 trials are tagged with Stomatognathic Diseases itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Stomatognathic Diseases trials start? (36)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 27 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Expanded access, Unknown)

Top of scale: 1,116

1991: 1 trials (Observational 1) 1992: 4 trials (Observational 2, Not applicable 1, Phase 3 1) 1993: 1 trials (Observational 1) 1994: 2 trials (Observational 1, Phase 3 1) 1995: 7 trials (Observational 4, Phase 2 2, Phase 1 1) 1996: 13 trials (Observational 2, Not applicable 3, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 4, Phase 1 1) 1997: 18 trials (Observational 2, Not applicable 1, Phase 3 1, Phase 2 11, Phase 1/2 2, Phase 1 1) 1998: 21 trials (Observational 5, Not applicable 3, Phase 4 1, Phase 3 3, Phase 2 7, Phase 1 2) 1999: 38 trials (Observational 3, Not applicable 7, Phase 4 1, Phase 3 5, Phase 2 14, Phase 1/2 1, Phase 1 7) 2000: 37 trials (Observational 4, Not applicable 6, Phase 4 1, Phase 3 8, Phase 2 9, Phase 1/2 2, Phase 1 7) 2001: 39 trials (Observational 7, Not applicable 6, Phase 4 2, Phase 3 6, Phase 2 8, Phase 1/2 1, Phase 1 9) 2002: 41 trials (Observational 6, Not applicable 6, Phase 4 3, Phase 3 5, Phase 2/3 1, Phase 2 13, Phase 1/2 3, Phase 1 4) 2003: 72 trials (Observational 11, Not applicable 13, Phase 4 6, Phase 3 15, Phase 2/3 2, Phase 2 17, Phase 1/2 2, Phase 1 6) 2004: 91 trials (Observational 16, Not applicable 18, Phase 4 5, Phase 3 18, Phase 2 19, Phase 1/2 1, Phase 1 14) 2005: 121 trials (Observational 25, Not applicable 26, Phase 4 6, Phase 3 15, Phase 2/3 3, Phase 2 28, Phase 1/2 4, Phase 1 14) 2006: 156 trials (Observational 34, Not applicable 28, Phase 4 16, Phase 3 33, Phase 2/3 2, Phase 2 30, Phase 1/2 3, Phase 1 10) 2007: 200 trials (Observational 43, Not applicable 49, Phase 4 18, Phase 3 29, Phase 2/3 3, Phase 2 34, Phase 1/2 8, Phase 1 16) 2008: 202 trials (Observational 45, Not applicable 51, Phase 4 17, Phase 3 33, Phase 2/3 6, Phase 2 29, Phase 1/2 7, Phase 1 14) 2009: 206 trials (Observational 38, Not applicable 52, Phase 4 17, Phase 3 25, Phase 2/3 8, Phase 2 42, Phase 1/2 12, Phase 1 12) 2010: 256 trials (Other 1, Observational 49, Not applicable 99, Phase 4 22, Phase 3 12, Phase 2/3 3, Phase 2 46, Phase 1/2 12, Phase 1 12) 2011: 256 trials (Observational 47, Not applicable 103, Phase 4 24, Phase 3 16, Phase 2/3 9, Phase 2 30, Phase 1/2 8, Phase 1 19) 2012: 320 trials (Other 1, Observational 64, Not applicable 127, Phase 4 31, Phase 3 28, Phase 2/3 6, Phase 2 39, Phase 1/2 8, Phase 1 16) 2013: 343 trials (Observational 58, Not applicable 156, Phase 4 38, Phase 3 21, Phase 2/3 12, Phase 2 36, Phase 1/2 9, Phase 1 13) 2014: 438 trials (Other 1, Observational 69, Not applicable 201, Phase 4 30, Phase 3 32, Phase 2/3 22, Phase 2 53, Phase 1/2 10, Phase 1 20) 2015: 498 trials (Observational 91, Not applicable 243, Phase 4 37, Phase 3 31, Phase 2/3 14, Phase 2 47, Phase 1/2 17, Phase 1 18) 2016: 605 trials (Observational 105, Not applicable 324, Phase 4 44, Phase 3 25, Phase 2/3 9, Phase 2 57, Phase 1/2 17, Phase 1 24) 2017: 626 trials (Other 1, Observational 104, Not applicable 368, Phase 4 30, Phase 3 26, Phase 2/3 10, Phase 2 56, Phase 1/2 12, Phase 1 19) 2018: 719 trials (Observational 165, Not applicable 379, Phase 4 32, Phase 3 38, Phase 2/3 13, Phase 2 59, Phase 1/2 14, Phase 1 19) 2019: 767 trials (Observational 150, Not applicable 441, Phase 4 31, Phase 3 26, Phase 2/3 5, Phase 2 72, Phase 1/2 11, Phase 1 31) 2020: 667 trials (Observational 146, Not applicable 353, Phase 4 29, Phase 3 24, Phase 2/3 12, Phase 2 64, Phase 1/2 12, Phase 1 27) 2021: 848 trials (Other 1, Observational 193, Not applicable 460, Phase 4 39, Phase 3 28, Phase 2/3 10, Phase 2 66, Phase 1/2 15, Phase 1 36) 2022: 873 trials (Observational 190, Not applicable 497, Phase 4 22, Phase 3 25, Phase 2/3 13, Phase 2 65, Phase 1/2 18, Phase 1 43) 2023: 1,027 trials (Observational 199, Not applicable 630, Phase 4 32, Phase 3 51, Phase 2/3 11, Phase 2 49, Phase 1/2 17, Phase 1 38) 2024: 1,116 trials (Observational 254, Not applicable 643, Phase 4 29, Phase 3 51, Phase 2/3 6, Phase 2 73, Phase 1/2 19, Phase 1 41) 2025: 1,073 trials (Observational 229, Not applicable 622, Phase 4 33, Phase 3 48, Phase 2/3 9, Phase 2 66, Phase 1/2 17, Phase 1 49)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 853
2025 1,073
2024 1,116
2023 1,027
2022 873
2021 848
2020 667
2019 767
2018 719
2017 626

Forecast of the full-year count, planned starts included, not rows of this table: about 1,100 trials starting in 2026 and about 1,000 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 10 percent and ran about 4 percent high against the count later registered; forecasts made before the year began were off by about 25 percent and ran about 15 percent low against the count later registered, and had about 7 percent more error than repeating last year's count. The part-way figures are from forecasts that used a multiple fitted only on earlier years. A stricter check that trains only on older years did not support adding planned starts for conditions of this size: it ran about 6 percent high against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 1,017 trials still running at the 2026-10-09 snapshot; registered median of 14 months across 7,487 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Stomatognathic Diseases trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 582
Phase 1/2 278
Phase 2 1,200
Phase 2/3 197
Phase 3 727
Phase 4 626
Not applicable 6,449
Observational 2,574
Expanded access 3
Unknown 4

How many Stomatognathic Diseases trials are recruiting? (11)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 819
Recruiting 1,248
Enrolling by invitation 160
Active, not recruiting 495
Available 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Stomatognathic Diseases trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Cancer Institute (NCI) 104
GlaxoSmithKline 97
Colgate Palmolive 86

Which drugs are being tested for Stomatognathic Diseases? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
CETUXIMAB 44
Platelet Rich Fibrin 42
PEMBROLIZUMAB 42

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Cisplatin 1 205
Gemcitabine/Gemzar 64
Low Level Laser Therapy 59
2% chlorhexidine 58
Radiation Therapy 58

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Stomatognathic Diseases trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Cardiac ischemia 729 1
Significant stenosis (PCI, CABG, conservative) 537 1
Dehydration 353 72
Dysphagia 293 49
Nausea 282 51

Which publications cover Stomatognathic Diseases? (27)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (7)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages