Condition (MeSH)
Acromegaly
ClinicalTrials.gov lists 200 trials for Acromegaly or a narrower condition beneath it. Ipsen has the most among industry and government lead sponsors, with 34.
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Trials per phase (log scale)
1 more section with rows
200 of the 200 trials are tagged with Acromegaly itself; the rest are tagged with a narrower condition beneath it.
When did Acromegaly trials start? (32)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 13
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 5 |
| 2025 | 5 |
| 2024 | 7 |
| 2023 | 6 |
| 2022 | 3 |
| 2021 | 4 |
| 2020 | 7 |
| 2019 | 8 |
| 2018 | 7 |
| 2017 | 5 |
Showing 10 of 32 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 6 trials starting in 2026 and about 5 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Acromegaly trials in? (9)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 10 |
| Phase 1/2 | 1 |
| Phase 2 | 25 |
| Phase 2/3 | 1 |
| Phase 3 | 32 |
| Phase 4 | 25 |
| Not applicable | 20 |
| Observational | 85 |
| Expanded access | 1 |
How many Acromegaly trials are recruiting? (9)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 4 |
| Recruiting | 12 |
| Active, not recruiting | 1 |
| Completed | 127 |
| Approved for marketing | 1 |
Showing 5 of 9 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Acromegaly trials? (8)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Ipsen | 34 |
| Novartis Pharmaceuticals | 15 |
| Pfizer | 7 |
| Crinetics Pharmaceuticals Inc. | 5 |
| Camurus AB | 4 |
Showing 5 of 8 sponsors.
Which drugs are being tested for Acromegaly? (2)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Pegvisomant | 17 |
| Paltusotine | 5 |
Interventions as named in the registry (13)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| LAR Octreotide | 29 |
| LAR Lanreotide | 11 |
| Pasireotide s.c. | 8 |
| Octreotide LAR | 6 |
| Lanreotide Autogel 120 mg | 3 |
Showing 5 of 13 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Acromegaly trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Cholelithiasis | 50 | 7 |
| Pituitary tumour benign | 24 | 5 |
| Pituitary tumour | 17 | 4 |
| Cholecystitis | 16 | 6 |
| Hyperglycaemia | 16 | 6 |
Showing 5 of 10 adverse events.
Which publications cover Acromegaly? (222)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Population Pharmacokinetic Analysis of an Octreotide Depot (CAM2029) in the Treatment of Acromegaly. | Clinical pharmacokinetics | 2025 | Yes |
| Octreotide Subcutaneous Depot for Acromegaly: A Randomized, Double-blind, Placebo-controlled Phase 3 Trial, ACROINNOVA 1. | The Journal of clinical endocrinology and metabolism | 2025 | Yes |
| Obstructive Sleep Apnea Screening and Effects of Surgery in Acromegaly: A Prospective Study. | Endocrinology and metabolism (Seoul, Korea) | 2024 | Yes |
| Development and evaluation of the Acromegaly Symptom Diary. | Journal of patient-reported outcomes | 2023 | Yes |
| Glucose metabolism, gut-brain hormones, and acromegaly treatment: an explorative single centre descriptive analysis. | Pituitary | 2023 | Yes |
Showing 5 of 222 publications.
Prevalence (63)
Shown in this order: jurisdiction, then disease name. Orphanet observation for the mapped ORPHA concept; the mapping relation column says whether that concept is exactly this condition or broader or narrower.
| Orphanet disease | Type | Class | Geography | Jurisdiction | Mapping relation |
|---|---|---|---|---|---|
| Acromegaly | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Unspecified |
| Acromegaly | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Exact |
| Acromegaly | Point prevalence | 1-9 / 100 000 | United Kingdom | GB | Exact |
| Acromegaly | Annual incidence | 1-9 / 100 000 | United States | US | Unspecified |
| Acromegaly | Annual incidence | 1-9 / 100 000 | United States | US | Exact |
Showing 5 of 63 prevalence observations.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Acromegaly | 963 | Exact | Orphanet Rare Disease Ontology (ORDO) |
| Acromegaly | 963 | Exact | Orphadata Science knowledge files, Product 1 |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: sub-conditions in mesh.