Condition (MeSH)
Adjustment Disorders
ClinicalTrials.gov lists 61 trials for Adjustment Disorders or a narrower condition beneath it.
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Trials per phase (log scale)
61 of the 61 trials are tagged with Adjustment Disorders itself; the rest are tagged with a narrower condition beneath it.
When did Adjustment Disorders trials start? (19)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 6
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 6 |
| 2024 | 2 |
| 2023 | 5 |
| 2022 | 4 |
| 2021 | 4 |
| 2020 | 3 |
| 2019 | 2 |
| 2018 | 4 |
| 2017 | 5 |
Showing 10 of 19 earlier years.
No forecast is made for this condition: it averages 3.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 7 trials still running at the 2026-10-09 snapshot; registered median of 30 months across 39 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Adjustment Disorders trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 3 |
| Phase 1/2 | 1 |
| Phase 2 | 7 |
| Phase 2/3 | 1 |
| Phase 3 | 2 |
| Phase 4 | 1 |
| Not applicable | 36 |
| Observational | 10 |
How many Adjustment Disorders trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 10 |
| Completed | 37 |
| Terminated | 3 |
| Unknown status | 10 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Adjustment Disorders trials? (3)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Linkoeping University | 2 |
| Momentum Data | 2 |
| Valenta Pharm JSC | 2 |
Which drugs are being tested for Adjustment Disorders? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| 3,4 Methylenedioxymethamphetamine | 2 |
| Afobazole | 1 |
| Duloxetine | 1 |
Interventions as named in the registry (9)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Propranolol PO | 3 |
| Ranquilon | 2 |
| Care as usual | 2 |
| Psilocybin therapy | 1 |
| No Interventions | 1 |
Showing 5 of 9 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Adjustment Disorders trials report? (4)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Diagnosed with colon cancer | 1 | 1 |
| Psychiatric hospitalization, hypomanic episode | 1 | 1 |
| Psychiatric hospitalization, increased PTSD symptoms | 1 | 1 |
| Psychiatric hospitalization, suicidal ideation | 1 | 1 |
Which publications cover Adjustment Disorders? (107)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Internet-Delivered Treatment for Stress-Related Disorders: A Randomized Controlled Superiority Trial of Cognitive Behavioral Therapy versus General Health Promotion. | Psychotherapy and psychosomatics | 2025 | Yes |
| Effectiveness and mediators of change of an online CBT intervention for students with adjustment disorder-study protocol for a randomized controlled trial. | Trials | 2023 | Yes |
| Meaning-making as a mediator of anxiety and depression reduction during cognitive behavioral therapy intervention in participants with adjustment disorders. | Clinical psychology & psychotherapy | 2021 | Yes |
| A guided Internet-delivered intervention for adjustment disorders: A randomized controlled trial. | Clinical psychology & psychotherapy | 2021 | Yes |
| Reliability and Validity of a German Standardized Diagnostic Interview Module for ICD-11 Adjustment Disorder. | Journal of traumatic stress | 2021 | Yes |
Showing 5 of 107 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.