Condition (MeSH)
Altitude Sickness
ClinicalTrials.gov lists 212 trials for Altitude Sickness or a narrower condition beneath it. United States Army Research Institute of Environmental Medicine has the most among industry and government lead sponsors, with 5.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase (log scale)
212 of the 212 trials are tagged with Altitude Sickness itself; the rest are tagged with a narrower condition beneath it.
When did Altitude Sickness trials start? (23)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 29
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 27 |
| 2025 | 9 |
| 2024 | 16 |
| 2023 | 24 |
| 2022 | 9 |
| 2021 | 13 |
| 2020 | 6 |
| 2019 | 10 |
| 2018 | 29 |
| 2017 | 6 |
Showing 10 of 23 earlier years.
Forecast of the full-year count, planned starts included, not rows of this table: about 32 trials starting in 2026 and about 19 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.
Prediction, not a registry value: median of 36 months from start to primary completion across 19 trials still running at the 2026-10-09 snapshot; registered median of 6 months across 127 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Altitude Sickness trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 11 |
| Phase 1/2 | 4 |
| Phase 2 | 5 |
| Phase 2/3 | 2 |
| Phase 3 | 7 |
| Phase 4 | 29 |
| Not applicable | 120 |
| Observational | 34 |
How many Altitude Sickness trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 22 |
| Recruiting | 17 |
| Enrolling by invitation | 2 |
| Active, not recruiting | 3 |
| Completed | 125 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Altitude Sickness trials? (2)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| United States Army Research Institute of Environmental Medicine | 5 |
| Tasly Pharmaceuticals, Inc. | 3 |
Which drugs are being tested for Altitude Sickness? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Methazolamide | 3 |
| EPOETIN ALFA | 2 |
| Prochlorperazine | 2 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Acetazolamide Pill | 29 |
| Hypoxia | 6 |
| Ibuprofen 2% | 5 |
| i.v. iron sucrose | 3 |
| Nifedipine XL | 3 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which publications cover Altitude Sickness? (205)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Self-monitoring symptoms and pulse oximetry to predict imminent altitude illness in patients with chronic obstructive pulmonary disease. | Pulmonology | 2026 | Yes |
| Sex-Specific Difference in Health-Related Altitude-Effects and Their Prevention by Acetazolamide. Data from a Randomized Controlled Trial. | High altitude medicine & biology | 2025 | Yes |
| Oxygen saturation and acute mountain sickness during repeated altitude exposures simulating high-altitude working schedules. | Scientific reports | 2025 | Yes |
| Effect of Acetazolamide on Pulmonary Hemodynamics and Right Heart Function in Healthy Adults Going to Altitude: A Randomized Controlled Trial. | Journal of the American Heart Association | 2025 | Yes |
| High Altitude Pulmonary Edema Response to Continuous Airway Positive Pressure: A Randomized Controlled Trial: The HAPER CAPER Trial. | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine | 2025 | Yes |
Showing 5 of 205 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.