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Condition (MeSH)

Angina Pectoris

ClinicalTrials.gov lists 1,057 trials for Angina Pectoris or a narrower condition beneath it. National Heart, Lung, and Blood Institute (NHLBI) has the most among industry and government lead sponsors, with 15.

MeSH D000787 Cardiovascular Diseases C14 C23
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Phase 1 Phase 1 20 Phase 1/2 Phase 1/2 9 Phase 2 Phase 2 72 Phase 2/3 Phase 2/3 15 Phase 3 Phase 3 92 Phase 4 Phase 4 165 Not applicable Not applicable 307 Observational Observational 377 Phase 1 Phase 1 20 Phase 1/2 Phase 1/2 9 Phase 2 Phase 2 72 Phase 2/3 Phase 2/3 15 Phase 3 Phase 3 92 Phase 4 Phase 4 165 Not applicable Not applicable 307 Observational Observational 377

Trials per phase (log scale)

452 of the 1,057 trials are tagged with Angina Pectoris itself; the rest are tagged with a narrower condition beneath it.

Get the Angina Pectoris report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Angina Pectoris trials start? (36)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 71

1991: 1 trials (Phase 3 1) 1992: 1 trials (Observational 1) 1993: 1 trials (Phase 3 1) 1994: 1 trials (Observational 1) 1995: 2 trials (Observational 1, Phase 3 1) 1996: 2 trials (Observational 1, Phase 4 1) 1997: 4 trials (Observational 2, Phase 4 2) 1998: 3 trials (Observational 2, Phase 2 1) 1999: 2 trials (Observational 1, Phase 4 1) 2000: 6 trials (Observational 3, Phase 4 1, Phase 2 1, Phase 1 1) 2001: 10 trials (Observational 4, Phase 4 1, Phase 3 2, Phase 2/3 1, Phase 2 2) 2002: 7 trials (Observational 2, Phase 4 2, Phase 3 2, Phase 2/3 1) 2003: 17 trials (Observational 3, Not applicable 3, Phase 4 2, Phase 3 5, Phase 2 3, Phase 1 1) 2004: 18 trials (Observational 3, Not applicable 6, Phase 4 2, Phase 3 4, Phase 2 2, Phase 1 1) 2005: 28 trials (Observational 6, Not applicable 3, Phase 4 5, Phase 3 8, Phase 2 5, Phase 1/2 1) 2006: 23 trials (Observational 8, Not applicable 6, Phase 4 1, Phase 3 6, Phase 2/3 1, Phase 2 1) 2007: 30 trials (Observational 6, Not applicable 8, Phase 4 4, Phase 3 3, Phase 2/3 1, Phase 2 7, Phase 1/2 1) 2008: 39 trials (Observational 9, Not applicable 4, Phase 4 8, Phase 3 7, Phase 2/3 3, Phase 2 5, Phase 1/2 1, Phase 1 2) 2009: 36 trials (Observational 10, Not applicable 8, Phase 4 8, Phase 3 2, Phase 2 4, Phase 1 4) 2010: 39 trials (Observational 11, Not applicable 11, Phase 4 8, Phase 3 3, Phase 2 4, Phase 1/2 1, Phase 1 1) 2011: 54 trials (Observational 12, Not applicable 13, Phase 4 18, Phase 3 4, Phase 2/3 1, Phase 2 3, Phase 1 3) 2012: 71 trials (Observational 30, Not applicable 14, Phase 4 11, Phase 3 8, Phase 2 7, Phase 1 1) 2013: 46 trials (Observational 17, Not applicable 12, Phase 4 8, Phase 3 8, Phase 1 1) 2014: 67 trials (Observational 20, Not applicable 19, Phase 4 13, Phase 3 7, Phase 2/3 1, Phase 2 6, Phase 1 1) 2015: 63 trials (Observational 29, Not applicable 10, Phase 4 10, Phase 3 1, Phase 2/3 1, Phase 2 9, Phase 1/2 3) 2016: 49 trials (Observational 10, Not applicable 23, Phase 4 13, Phase 2 2, Phase 1/2 1) 2017: 45 trials (Observational 21, Not applicable 15, Phase 4 8, Phase 2 1) 2018: 41 trials (Observational 18, Not applicable 10, Phase 4 9, Phase 3 3, Phase 1 1) 2019: 40 trials (Observational 15, Not applicable 17, Phase 4 2, Phase 3 3, Phase 2 3) 2020: 49 trials (Observational 19, Not applicable 18, Phase 4 7, Phase 2/3 1, Phase 2 3, Phase 1/2 1) 2021: 51 trials (Observational 20, Not applicable 24, Phase 4 5, Phase 3 1, Phase 2/3 1) 2022: 34 trials (Observational 14, Not applicable 14, Phase 4 3, Phase 3 2, Phase 1 1) 2023: 48 trials (Observational 22, Not applicable 18, Phase 4 4, Phase 3 3, Phase 1 1) 2024: 40 trials (Observational 15, Not applicable 19, Phase 4 2, Phase 3 1, Phase 2/3 2, Phase 2 1) 2025: 36 trials (Observational 16, Not applicable 14, Phase 4 2, Phase 3 1, Phase 2 2, Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 38
2025 36
2024 40
2023 48
2022 34
2021 51
2020 49
2019 40
2018 41
2017 45

Forecast of the full-year count, planned starts included, not rows of this table: about 47 trials starting in 2026 and about 42 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 71 trials still running at the 2026-10-09 snapshot; registered median of 26 months across 591 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Angina Pectoris trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 20
Phase 1/2 9
Phase 2 72
Phase 2/3 15
Phase 3 92
Phase 4 165
Not applicable 307
Observational 377

How many Angina Pectoris trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 39
Recruiting 95
Enrolling by invitation 12
Active, not recruiting 46
Completed 521

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Angina Pectoris trials? (5)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Heart, Lung, and Blood Institute (NHLBI) 15
CardioDx 11
AstraZeneca 7
Gilead Sciences 7
Abbott Medical Devices 6

Which drugs are being tested for Angina Pectoris? (8)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Ranolazine 22
ATORVASTATIN 12
Nitroglycerin 7
Nicorandil 6
ROSUVASTATIN 5

Interventions as named in the registry (7)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Clopidogrel 75 25
EC Aspirin 20
Ticagrelor (Brilique) 90 18
Prasugel 6
Ivabradine Pill 5

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Angina Pectoris trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 1,327 22
Angina pectoris 683 19
Osteoarthritis 596 12
Atrial Fibrillation 514 5
Syncope 476 17

Which publications cover Angina Pectoris? (873)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (3)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages