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Condition (MeSH)

Myocardial Ischemia

ClinicalTrials.gov lists 10,385 trials for Myocardial Ischemia or a narrower condition beneath it. National Heart, Lung, and Blood Institute (NHLBI) has the most among industry and government lead sponsors, with 245.

MeSH D017202 Cardiovascular Diseases C14
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Phase 1 Phase 1 229 Phase 1/2 Phase 1/2 114 Phase 2 Phase 2 531 Phase 2/3 Phase 2/3 134 Phase 3 Phase 3 739 Phase 4 Phase 4 1,368 Not applicable Not applicable 3,369 Observational Observational 3,896 Phase 1 Phase 1 229 Phase 1/2 Phase 1/2 114 Phase 2 Phase 2 531 Phase 2/3 Phase 2/3 134 Phase 3 Phase 3 739 Phase 4 Phase 4 1,368 Not applicable Not applicable 3,369 Observational Observational 3,896

Trials per phase (log scale)

1 more section with rows

1,093 of the 10,385 trials are tagged with Myocardial Ischemia itself; the rest are tagged with a narrower condition beneath it.

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The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Myocardial Ischemia trials start? (37)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 16 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 519

1990: 11 trials (Observational 9, Phase 3 1, Phase 2 1) 1991: 24 trials (Observational 18, Not applicable 1, Phase 3 4, Phase 2 1) 1992: 23 trials (Observational 16, Not applicable 1, Phase 3 6) 1993: 14 trials (Observational 10, Not applicable 1, Phase 3 2, Phase 2 1) 1994: 22 trials (Observational 15, Phase 4 1, Phase 3 5, Phase 2 1) 1995: 19 trials (Observational 14, Phase 3 5) 1996: 20 trials (Observational 12, Not applicable 4, Phase 4 1, Phase 3 3) 1997: 20 trials (Observational 10, Not applicable 2, Phase 4 3, Phase 3 2, Phase 2 3) 1998: 39 trials (Observational 25, Not applicable 2, Phase 4 2, Phase 3 7, Phase 2 3) 1999: 43 trials (Observational 17, Not applicable 6, Phase 4 5, Phase 3 9, Phase 2/3 1, Phase 2 4, Phase 1/2 1) 2000: 51 trials (Observational 26, Not applicable 8, Phase 4 2, Phase 3 7, Phase 2/3 1, Phase 2 4, Phase 1/2 2, Phase 1 1) 2001: 71 trials (Observational 31, Not applicable 9, Phase 4 12, Phase 3 10, Phase 2/3 2, Phase 2 7) 2002: 89 trials (Observational 18, Not applicable 18, Phase 4 18, Phase 3 19, Phase 2/3 5, Phase 2 6, Phase 1/2 1, Phase 1 4) 2003: 172 trials (Observational 56, Not applicable 24, Phase 4 25, Phase 3 38, Phase 2/3 6, Phase 2 12, Phase 1/2 6, Phase 1 5) 2004: 169 trials (Observational 42, Not applicable 27, Phase 4 44, Phase 3 25, Phase 2/3 7, Phase 2 17, Phase 1/2 4, Phase 1 3) 2005: 207 trials (Observational 48, Not applicable 43, Phase 4 40, Phase 3 40, Phase 2/3 5, Phase 2 19, Phase 1/2 6, Phase 1 6) 2006: 314 trials (Observational 87, Not applicable 57, Phase 4 74, Phase 3 41, Phase 2/3 5, Phase 2 32, Phase 1/2 1, Phase 1 17) 2007: 323 trials (Observational 92, Not applicable 75, Phase 4 60, Phase 3 28, Phase 2/3 9, Phase 2 39, Phase 1/2 8, Phase 1 12) 2008: 343 trials (Observational 99, Not applicable 81, Phase 4 58, Phase 3 42, Phase 2/3 15, Phase 2 26, Phase 1/2 9, Phase 1 13) 2009: 394 trials (Observational 116, Not applicable 103, Phase 4 79, Phase 3 34, Phase 2/3 11, Phase 2 29, Phase 1/2 7, Phase 1 15) 2010: 442 trials (Observational 164, Not applicable 106, Phase 4 87, Phase 3 37, Phase 2/3 3, Phase 2 19, Phase 1/2 11, Phase 1 15) 2011: 433 trials (Observational 130, Not applicable 124, Phase 4 82, Phase 3 40, Phase 2/3 7, Phase 2 33, Phase 1/2 6, Phase 1 11) 2012: 442 trials (Observational 153, Not applicable 126, Phase 4 86, Phase 3 32, Phase 2/3 1, Phase 2 27, Phase 1/2 4, Phase 1 13) 2013: 427 trials (Observational 139, Not applicable 141, Phase 4 60, Phase 3 43, Phase 2/3 4, Phase 2 25, Phase 1/2 1, Phase 1 14) 2014: 450 trials (Observational 161, Not applicable 145, Phase 4 82, Phase 3 23, Phase 2/3 5, Phase 2 22, Phase 1/2 2, Phase 1 10) 2015: 466 trials (Observational 169, Not applicable 156, Phase 4 71, Phase 3 21, Phase 2/3 5, Phase 2 27, Phase 1/2 10, Phase 1 7) 2016: 475 trials (Observational 195, Not applicable 181, Phase 4 58, Phase 3 13, Phase 2/3 5, Phase 2 13, Phase 1/2 5, Phase 1 5) 2017: 477 trials (Observational 213, Not applicable 168, Phase 4 61, Phase 3 8, Phase 2/3 5, Phase 2 14, Phase 1/2 3, Phase 1 5) 2018: 468 trials (Observational 187, Not applicable 179, Phase 4 52, Phase 3 21, Phase 2/3 2, Phase 2 16, Phase 1/2 3, Phase 1 8) 2019: 448 trials (Observational 198, Not applicable 161, Phase 4 42, Phase 3 17, Phase 2/3 4, Phase 2 13, Phase 1/2 3, Phase 1 10) 2020: 441 trials (Observational 201, Not applicable 158, Phase 4 37, Phase 3 14, Phase 2/3 4, Phase 2 17, Phase 1/2 4, Phase 1 6) 2021: 519 trials (Observational 201, Not applicable 208, Phase 4 52, Phase 3 23, Phase 2/3 6, Phase 2 16, Phase 1/2 5, Phase 1 8) 2022: 508 trials (Observational 212, Not applicable 218, Phase 4 35, Phase 3 14, Phase 2 16, Phase 1/2 3, Phase 1 10) 2023: 479 trials (Observational 201, Not applicable 209, Phase 4 37, Phase 3 18, Phase 2/3 1, Phase 2 7, Phase 1 6) 2024: 483 trials (Observational 201, Not applicable 202, Phase 4 26, Phase 3 18, Phase 2/3 6, Phase 2 20, Phase 1/2 2, Phase 1 8) 2025: 454 trials (Observational 178, Not applicable 194, Phase 4 34, Phase 3 14, Phase 2/3 2, Phase 2 17, Phase 1/2 4, Phase 1 11)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 434
2025 454
2024 483
2023 479
2022 508
2021 519
2020 441
2019 448
2018 468
2017 477

Forecast of the full-year count, planned starts included, not rows of this table: about 510 trials starting in 2026 and about 490 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 13 percent and ran about 12 percent low against the count later registered; forecasts made before the year began were off by about 19 percent and ran about 17 percent low against the count later registered, and had about the same error as repeating last year's count. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 638 trials still running at the 2026-10-09 snapshot; registered median of 25 months across 5,939 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Myocardial Ischemia trials in? (9)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 229
Phase 1/2 114
Phase 2 531
Phase 2/3 134
Phase 3 739
Phase 4 1,368
Not applicable 3,369
Observational 3,896
Expanded access 5

How many Myocardial Ischemia trials are recruiting? (11)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 444
Recruiting 1,025
Enrolling by invitation 66
Active, not recruiting 364
Available 2

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Myocardial Ischemia trials? (5)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
National Heart, Lung, and Blood Institute (NHLBI) 245
Abbott Medical Devices 87
China National Center for Cardiovascular Diseases 86
AstraZeneca 74
Boston Scientific Corporation 53

Which drugs are being tested for Myocardial Ischemia? (9)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
ATORVASTATIN 101
ROSUVASTATIN 70
Rivaroxaban 41
Ranolazine 35
Regadenoson 31

Interventions as named in the registry (6)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Clopidogrel 75 242
Ticagrelor (Brilique) 90 193
EC Aspirin 142
Prasugel 97
Colchicines 52

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Myocardial Ischemia trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Other 17,761 12
Angina pectoris 8,595 128
Angina unstable 8,060 115
Pneumonia 6,244 157
MVE 6,060 1

Which publications cover Myocardial Ischemia? (1,783)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Sub-conditions in MeSH (5)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and rare-disease identity.

Browse all condition evidence pages