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Condition (MeSH)

Anodontia

ClinicalTrials.gov lists 99 trials for Anodontia or a narrower condition beneath it.

MeSH D000848 Stomatognathic Diseases C07 C16 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 1 Phase 3 Phase 3 1 Phase 4 Phase 4 3 Not applicable Not applicable 71 Observational Observational 23 Phase 1 Phase 1 1 Phase 3 Phase 3 1 Phase 4 Phase 4 3 Not applicable Not applicable 71 Observational Observational 23

Trials per phase (log scale)

99 of the 99 trials are tagged with Anodontia itself; the rest are tagged with a narrower condition beneath it.

Get the Anodontia report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Anodontia trials start? (21)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 16

2002: 1 trials (Not applicable 1) 2003: 1 trials (Observational 1) 2005: 1 trials (Not applicable 1) 2009: 1 trials (Not applicable 1) 2010: 3 trials (Observational 2, Not applicable 1) 2011: 4 trials (Observational 1, Not applicable 1, Phase 4 1, Phase 3 1) 2012: 4 trials (Observational 1, Not applicable 2, Phase 4 1) 2013: 1 trials (Not applicable 1) 2014: 4 trials (Not applicable 4) 2015: 2 trials (Observational 1, Phase 4 1) 2016: 2 trials (Not applicable 2) 2017: 6 trials (Observational 2, Not applicable 4) 2018: 6 trials (Observational 2, Not applicable 4) 2019: 9 trials (Observational 3, Not applicable 6) 2020: 3 trials (Not applicable 3) 2021: 6 trials (Not applicable 6) 2022: 16 trials (Observational 4, Not applicable 11, Phase 1 1) 2023: 8 trials (Observational 3, Not applicable 5) 2024: 5 trials (Observational 1, Not applicable 4) 2025: 13 trials (Not applicable 13)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 1
2025 13
2024 5
2023 8
2022 16
2021 6
2020 3
2019 9
2018 6
2017 6

Forecast of the full-year count, planned starts included, not rows of this table: about 3 trials starting in 2026 and about 7 in 2027, the average of the 24 months through September, counted as registered and carried forward. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 28 percent and ran about 20 percent low against the count later registered; forecasts made before the year began were off by about 39 percent and ran about 37 percent low against the count later registered. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 8 trials still running at the 2026-10-09 snapshot; registered median of 17 months across 55 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Anodontia trials in? (5)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 1
Phase 3 1
Phase 4 3
Not applicable 71
Observational 23

How many Anodontia trials are recruiting? (8)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 7
Recruiting 9
Enrolling by invitation 1
Active, not recruiting 5
Completed 47

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Anodontia trials? (2)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Institut Straumann AG 2
Z-Systems 2

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Bio-Oss 2
Hyaluronic acid 1% 2
Enamel Matrix Derivative (Emdogain) 1
sandblasted, and acid-etched 1
Radiographic Evaluation 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Anodontia trials report? (3)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Ablation of a cyste in the femur 1 1
Death 1 1
Kneeoperation 1 1

Which publications cover Anodontia? (33)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Rare-disease identity (2)

Shown in this order: exact, broader, narrower, other.

Rare-disease identity
Orphanet disease ORPHA code Relation Source
Anodontia 99797 Exact Orphanet Rare Disease Ontology (ORDO)
Anodontia 99797 Exact Orphadata Science knowledge files, Product 1

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: prevalence and sub-conditions in mesh.

Browse all condition evidence pages