Condition (MeSH)
Anxiety, Separation
ClinicalTrials.gov lists 59 trials for Anxiety, Separation or a narrower condition beneath it. National Institute of Mental Health (NIMH) has the most among industry and government lead sponsors, with 3.
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Trials per phase (log scale)
59 of the 59 trials are tagged with Anxiety, Separation itself; the rest are tagged with a narrower condition beneath it.
When did Anxiety, Separation trials start? (24)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 2 |
| 2025 | 4 |
| 2024 | 2 |
| 2023 | 1 |
| 2022 | 1 |
| 2021 | 3 |
| 2020 | 2 |
| 2019 | 1 |
| 2018 | 2 |
| 2017 | 1 |
Showing 10 of 24 earlier years.
No forecast is made for this condition: it averages 2.0 trial starts a year over the five years to September, under the 5 a year the method needs.
Prediction, not a registry value: median of 36 months from start to primary completion across 6 trials still running at the 2026-10-09 snapshot; registered median of 38 months across 44 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Anxiety, Separation trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 1/2 | 2 |
| Phase 2 | 5 |
| Phase 2/3 | 1 |
| Phase 3 | 4 |
| Phase 4 | 2 |
| Not applicable | 39 |
| Observational | 4 |
How many Anxiety, Separation trials are recruiting? (8)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 1 |
| Recruiting | 4 |
| Active, not recruiting | 4 |
| Completed | 39 |
| Suspended | 1 |
Showing 5 of 8 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Anxiety, Separation trials? (1)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| National Institute of Mental Health (NIMH) | 3 |
Which drugs are being tested for Anxiety, Separation? (3)
Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.
| Drug | Trials |
|---|---|
| Fluvoxamine | 2 |
| METHYLPHENIDATE | 1 |
| DEXMEDETOMIDINE | 1 |
Interventions as named in the registry (12)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| Treatment As Usual | 8 |
| Sertralin | 3 |
| S-ketamine 2 | 1 |
| S-Ketamine 0.5 | 1 |
| TAU | 1 |
Showing 5 of 12 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Anxiety, Separation trials report? (3)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Oppositional-Defiant Behavior | 1 | 1 |
| Tonsillectomy | 1 | 1 |
| Worsening of Behavior | 1 | 1 |
Which publications cover Anxiety, Separation? (69)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Effect of transportation method on preoperative anxiety in children: a randomized controlled trial. | Korean journal of anesthesiology | 2020 | Yes |
| Long-term effectiveness of cognitive behavioral therapy for youth with anxiety disorders. | Journal of anxiety disorders | 2018 | Yes |
| Extended Release Guanfacine in Pediatric Anxiety Disorders: A Pilot, Randomized, Placebo-Controlled Trial. | Journal of child and adolescent psychopharmacology | 2017 | Yes |
| A randomized controlled pilot trial of vilazodone for adult separation anxiety disorder. | Depression and anxiety | 2017 | Yes |
| Salivary oxytocin in clinically anxious youth: Associations with separation anxiety and family accommodation. | Psychoneuroendocrinology | 2016 | Yes |
Showing 5 of 69 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.