Condition (MeSH)
Blepharoptosis
ClinicalTrials.gov lists 72 trials for Blepharoptosis or a narrower condition beneath it. Sheba Medical Center has the most among industry and government lead sponsors, with 4.
Search trials, drugs, companies and investigators, and follow each one to the others. Individual plan, $249/seat/mo. Card required.
Trials per phase
72 of the 72 trials are tagged with Blepharoptosis itself; the rest are tagged with a narrower condition beneath it.
When did Blepharoptosis trials start? (20)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 1
- Phase 1/2
- Phase 2
- Phase 2/3
- Phase 3
- Phase 4
- Not applicable
- Observational
Top of scale: 7
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 4 |
| 2025 | 5 |
| 2024 | 4 |
| 2023 | 4 |
| 2022 | 4 |
| 2021 | 5 |
| 2020 | 4 |
| 2019 | 5 |
| 2018 | 7 |
| 2017 | 5 |
Showing 10 of 20 earlier years.
No forecast is made for this condition: it averages 3.6 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 4 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Blepharoptosis trials in? (8)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 1 | 2 |
| Phase 1/2 | 2 |
| Phase 2 | 2 |
| Phase 2/3 | 3 |
| Phase 3 | 4 |
| Phase 4 | 12 |
| Not applicable | 32 |
| Observational | 15 |
How many Blepharoptosis trials are recruiting? (7)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Not yet recruiting | 4 |
| Recruiting | 8 |
| Active, not recruiting | 1 |
| Completed | 37 |
| Terminated | 4 |
Showing 5 of 7 statuses.
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Blepharoptosis trials? (5)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Sheba Medical Center | 4 |
| RVL Pharmaceuticals, Inc. | 3 |
| Santen Pharmaceutical Co., Ltd. | 2 |
| 1st SurgiConcept | 1 |
| Aesculap AG | 1 |
Interventions as named in the registry (15)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| RVL-1201 | 3 |
| Vehicle Ophthalmic Solution | 2 |
| type A botulinum toxin | 2 |
| STN1013800 ophthalmic solution | 2 |
| Brimonidine tartrate ophthalmic solution 0.025% | 2 |
Showing 5 of 15 interventions.
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Blepharoptosis trials report? (7)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| dehiscence | 5 | 1 |
| seroma | 5 | 1 |
| Arthralgia | 1 | 1 |
| Cerebrovascular accident | 1 | 1 |
| Guillan-Barre syndrome | 1 | 1 |
Showing 5 of 7 adverse events.
Which publications cover Blepharoptosis? (86)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Levator Muscle Complex Exploration During Surgery for Simple Severe Congenital Ptosis. | Ophthalmic plastic and reconstructive surgery | 2026 | Yes |
| A Single-Center Sham and Active-Controlled Double-Blind Randomized Crossover Trial of the Magnetic Levator Prosthesis for Severe Blepharoptosis. | Translational vision science & technology | 2025 | Yes |
| Efficacy and Safety of a Magnetic Device for Temporary Management of Blepharoptosis: Single-Arm Open-Label Trial. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | 2025 | Yes |
| Congenital ptosis with aponeurotic maldevelopment: clinical and surgical perspectives : Aponeurotic maldevelopment in congenital ptosis. | International ophthalmology | 2024 | Yes |
| Digital analysis of unilateral ptosis repair: external levator advancement vs. Müller's muscle conjunctival resection. | Arquivos brasileiros de oftalmologia | 2024 | Yes |
Showing 5 of 86 publications.
Rare-disease identity (2)
Shown in this order: exact, broader, narrower, other.
| Orphanet disease | ORPHA code | Relation | Source |
|---|---|---|---|
| Rare disorder with ptosis | 98578 | Exact | Orphadata Science knowledge files, Product 1 |
| Rare disorder with ptosis | 98578 | Exact | Orphanet Rare Disease Ontology (ORDO) |
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence and sub-conditions in mesh.