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Condition (MeSH)

Body Temperature Changes

ClinicalTrials.gov lists 1,143 trials for Body Temperature Changes or a narrower condition beneath it.

MeSH D001832 Pathological Conditions, Signs and Symptoms C23
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Phase 1 Phase 1 34 Phase 1/2 Phase 1/2 16 Phase 2 Phase 2 56 Phase 2/3 Phase 2/3 16 Phase 3 Phase 3 85 Phase 4 Phase 4 72 Not applicable Not applicable 578 Observational Observational 284 Phase 1 Phase 1 34 Phase 1/2 Phase 1/2 16 Phase 2 Phase 2 56 Phase 2/3 Phase 2/3 16 Phase 3 Phase 3 85 Phase 4 Phase 4 72 Not applicable Not applicable 578 Observational Observational 284

Trials per phase (log scale)

2 more sections with rows

97 of the 1,143 trials are tagged with Body Temperature Changes itself; the rest are tagged with a narrower condition beneath it.

Get the Body Temperature Changes report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Body Temperature Changes trials start? (32)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 3 trials are registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational
  • Other (Unknown)

Top of scale: 67

1993: 1 trials (Phase 3 1) 1994: 1 trials (Observational 1) 1997: 4 trials (Phase 3 1, Phase 1 3) 1998: 1 trials (Phase 1 1) 1999: 5 trials (Not applicable 1, Phase 3 4) 2000: 2 trials (Phase 3 2) 2001: 4 trials (Not applicable 1, Phase 4 1, Phase 3 2) 2002: 11 trials (Observational 1, Not applicable 4, Phase 4 1, Phase 3 4, Phase 1/2 1) 2003: 13 trials (Observational 1, Not applicable 2, Phase 4 3, Phase 3 1, Phase 2 3, Phase 1/2 2, Phase 1 1) 2004: 10 trials (Observational 2, Not applicable 2, Phase 4 1, Phase 3 2, Phase 2 2, Phase 1/2 1) 2005: 15 trials (Observational 4, Not applicable 5, Phase 4 2, Phase 3 4) 2006: 24 trials (Observational 5, Not applicable 4, Phase 4 2, Phase 3 5, Phase 2/3 1, Phase 2 3, Phase 1/2 1, Phase 1 3) 2007: 35 trials (Observational 6, Not applicable 9, Phase 4 2, Phase 3 11, Phase 2 3, Phase 1 4) 2008: 44 trials (Observational 12, Not applicable 13, Phase 4 10, Phase 3 6, Phase 2/3 1, Phase 2 1, Phase 1 1) 2009: 31 trials (Observational 5, Not applicable 13, Phase 4 6, Phase 3 2, Phase 2/3 2, Phase 2 2, Phase 1 1) 2010: 56 trials (Observational 11, Not applicable 22, Phase 4 4, Phase 3 8, Phase 2/3 3, Phase 2 6, Phase 1 2) 2011: 26 trials (Observational 8, Not applicable 9, Phase 4 4, Phase 3 2, Phase 2/3 1, Phase 2 1, Phase 1 1) 2012: 47 trials (Observational 10, Not applicable 18, Phase 4 4, Phase 3 3, Phase 2/3 1, Phase 2 7, Phase 1/2 3, Phase 1 1) 2013: 47 trials (Observational 10, Not applicable 20, Phase 4 4, Phase 3 7, Phase 2/3 2, Phase 2 1, Phase 1/2 1, Phase 1 2) 2014: 54 trials (Observational 17, Not applicable 27, Phase 4 2, Phase 3 3, Phase 2 3, Phase 1/2 1, Phase 1 1) 2015: 48 trials (Observational 14, Not applicable 23, Phase 4 5, Phase 3 3, Phase 2 3) 2016: 56 trials (Observational 15, Not applicable 30, Phase 4 2, Phase 3 4, Phase 2 3, Phase 1/2 1, Phase 1 1) 2017: 46 trials (Observational 14, Not applicable 23, Phase 4 4, Phase 3 1, Phase 2/3 1, Phase 2 2, Phase 1 1) 2018: 62 trials (Observational 19, Not applicable 36, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 2, Phase 1/2 1, Phase 1 1) 2019: 64 trials (Observational 19, Not applicable 39, Phase 4 3, Phase 3 1, Phase 2 1, Phase 1 1) 2020: 51 trials (Observational 15, Not applicable 30, Phase 4 2, Phase 3 1, Phase 2 2, Phase 1/2 1) 2021: 66 trials (Observational 25, Not applicable 35, Phase 4 1, Phase 3 1, Phase 2 3, Phase 1 1) 2022: 65 trials (Observational 18, Not applicable 42, Phase 4 1, Phase 3 1, Phase 1/2 1, Phase 1 2) 2023: 62 trials (Observational 18, Not applicable 39, Phase 4 2, Phase 2/3 1, Phase 1/2 1, Phase 1 1) 2024: 67 trials (Other 1, Observational 12, Not applicable 46, Phase 4 1, Phase 3 3, Phase 2 2, Phase 1 2) 2025: 67 trials (Observational 11, Not applicable 47, Phase 4 1, Phase 3 1, Phase 2/3 1, Phase 2 3, Phase 1/2 1, Phase 1 2)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 50
2025 67
2024 67
2023 62
2022 65
2021 66
2020 51
2019 64
2018 62
2017 46

Forecast of the full-year count, planned starts included, not rows of this table: about 63 trials starting in 2026 and about 63 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 36 months from start to primary completion across 58 trials still running at the 2026-10-09 snapshot; registered median of 15 months across 750 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Body Temperature Changes trials in? (10)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 34
Phase 1/2 16
Phase 2 56
Phase 2/3 16
Phase 3 85
Phase 4 72
Not applicable 578
Observational 284
Expanded access 1
Unknown 1

How many Body Temperature Changes trials are recruiting? (10)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 42
Recruiting 100
Enrolling by invitation 9
Active, not recruiting 22
Completed 669

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Body Temperature Changes trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
Assaf-Harofeh Medical Center 9
National Cancer Institute (NCI) 9
Medtronic Surgical Technologies 7

Interventions as named in the registry (15)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
A3: Acetaminophen (Tylenol caplets®, from Janssen-Cilag, S.A. de C.V.) 38
Ibuprofen 2% 15
Radiotherapy 9
Standard Care 7
Cisplatin 1 5

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Body Temperature Changes trials report? (10)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Pneumonia 220 14
SAEs and other adverse events 160 1
Sepsis syndrome 120 1
Gastroenteritis 114 4
neonatal infections 69 1

Sub-conditions in MeSH (3)

MeSH descendants one level down with at least one trial, most trials first.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: publications, prevalence, and rare-disease identity.

Browse all condition evidence pages