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Condition (MeSH)

Carpal Tunnel Syndrome

ClinicalTrials.gov lists 577 trials for Carpal Tunnel Syndrome or a narrower condition beneath it.

MeSH D002349 Nervous System Diseases C10 C26 Listed by Orphanet as a rare disease
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Phase 1 Phase 1 12 Phase 1/2 Phase 1/2 7 Phase 2 Phase 2 20 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 10 Phase 4 Phase 4 41 Not applicable Not applicable 350 Observational Observational 132 Phase 1 Phase 1 12 Phase 1/2 Phase 1/2 7 Phase 2 Phase 2 20 Phase 2/3 Phase 2/3 5 Phase 3 Phase 3 10 Phase 4 Phase 4 41 Not applicable Not applicable 350 Observational Observational 132

Trials per phase (log scale)

577 of the 577 trials are tagged with Carpal Tunnel Syndrome itself; the rest are tagged with a narrower condition beneath it.

Get the Carpal Tunnel Syndrome report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Carpal Tunnel Syndrome trials start? (27)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year. 1 trial is registered to start in 2027 or later, and not listed here.

Trials over time, by phase

  • Phase 1
  • Phase 1/2
  • Phase 2
  • Phase 2/3
  • Phase 3
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 66

1997: 1 trials (Not applicable 1) 1999: 1 trials (Phase 2 1) 2002: 3 trials (Observational 2, Not applicable 1) 2003: 5 trials (Observational 2, Not applicable 1, Phase 4 1, Phase 3 1) 2004: 3 trials (Not applicable 1, Phase 4 2) 2005: 1 trials (Phase 3 1) 2006: 7 trials (Observational 1, Not applicable 2, Phase 3 1, Phase 2 2, Phase 1/2 1) 2007: 7 trials (Observational 1, Not applicable 3, Phase 1/2 3) 2008: 5 trials (Observational 1, Not applicable 2, Phase 2/3 1, Phase 1/2 1) 2009: 12 trials (Observational 2, Not applicable 6, Phase 4 1, Phase 3 1, Phase 2 1, Phase 1 1) 2010: 9 trials (Observational 2, Not applicable 4, Phase 3 1, Phase 2 2) 2011: 8 trials (Observational 3, Not applicable 3, Phase 3 1, Phase 1 1) 2012: 11 trials (Observational 2, Not applicable 5, Phase 4 2, Phase 2 2) 2013: 17 trials (Observational 2, Not applicable 9, Phase 4 4, Phase 2 2) 2014: 15 trials (Observational 4, Not applicable 9, Phase 4 1, Phase 2 1) 2015: 15 trials (Observational 3, Not applicable 10, Phase 4 1, Phase 2/3 1) 2016: 30 trials (Observational 9, Not applicable 13, Phase 4 2, Phase 2/3 1, Phase 2 2, Phase 1/2 1, Phase 1 2) 2017: 16 trials (Observational 2, Not applicable 11, Phase 4 1, Phase 2 1, Phase 1 1) 2018: 28 trials (Observational 1, Not applicable 20, Phase 4 3, Phase 3 1, Phase 1 3) 2019: 29 trials (Observational 7, Not applicable 18, Phase 4 3, Phase 1 1) 2020: 33 trials (Observational 8, Not applicable 17, Phase 4 5, Phase 3 1, Phase 2/3 1, Phase 1/2 1) 2021: 44 trials (Observational 12, Not applicable 30, Phase 4 2) 2022: 54 trials (Observational 7, Not applicable 40, Phase 4 4, Phase 2 2, Phase 1 1) 2023: 66 trials (Observational 21, Not applicable 40, Phase 4 3, Phase 3 1, Phase 2/3 1) 2024: 50 trials (Observational 14, Not applicable 36) 2025: 57 trials (Observational 13, Not applicable 36, Phase 4 5, Phase 2 2, Phase 1 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 48
2025 57
2024 50
2023 66
2022 54
2021 44
2020 33
2019 29
2018 28
2017 16

Forecast of the full-year count, planned starts included, not rows of this table: about 61 trials starting in 2026 and about 59 in 2027, the average of the 24 months through September, counted as registered and carried forward, with about 0.7 times the starts already registered for the rest of 2026 added. The rows of this table count trials registered so far with a start date in the year, planned starts included; the forecast looks ahead to the count for the whole year, so it is not the same measure. In backtests on conditions of this size, forecasts made part-way through the year were typically off by about 15 percent and ran about 1 percent high against the count later registered; forecasts made before the year began were off by about 26 percent and ran about 20 percent low against the count later registered. The part-way figures are from forecasts that used a multiple fitted only on earlier years. These figures rest on a few years of history (target years from 2018 to 2025, varying by figure), place each condition as it is mapped today rather than as it was then, and score against a count for the newest year that was still being revised. Only condition series were scored.

Prediction, not a registry value: median of 34 months from start to primary completion across 44 trials still running at the 2026-10-09 snapshot; registered median of 12 months across 357 trials with a primary completion typed Actual. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Carpal Tunnel Syndrome trials in? (8)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 12
Phase 1/2 7
Phase 2 20
Phase 2/3 5
Phase 3 10
Phase 4 41
Not applicable 350
Observational 132

How many Carpal Tunnel Syndrome trials are recruiting? (9)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 48
Recruiting 50
Enrolling by invitation 8
Active, not recruiting 13
Completed 338

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which drugs are being tested for Carpal Tunnel Syndrome? (3)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
METHYLPREDNISOLONE 7
Corticosteroid 5
Ibuprofen Arginine 4

Interventions as named in the registry (12)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
[PRP] platelet rich plasma 10
L:Lidocaine 9
Exercise 7
Triamcinolone Acetonide alone 6
Gabapentin 6% 6

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which serious adverse events do Carpal Tunnel Syndrome trials report? (5)

Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.

Serious adverse events in this condition's trials
Adverse event Subjects affected Trials
Other 3 1
Arthritis 2 1
Fracture 1 1
Myocardial infarction 1 1
Nerve Injury - Digital-Median 1 1

Which publications cover Carpal Tunnel Syndrome? (708)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: lead sponsors, prevalence, rare-disease identity, and sub-conditions in mesh.

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