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Condition (MeSH)

Catatonia

ClinicalTrials.gov lists 22 trials for Catatonia or a narrower condition beneath it.

MeSH D002389 Nervous System Diseases C10 C23
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Phase 1 Phase 1 2 Phase 2 Phase 2 2 Phase 4 Phase 4 1 Not applicable Not applicable 9 Observational Observational 8 Phase 1 Phase 1 2 Phase 2 Phase 2 2 Phase 4 Phase 4 1 Not applicable Not applicable 9 Observational Observational 8

Trials per phase

22 of the 22 trials are tagged with Catatonia itself; the rest are tagged with a narrower condition beneath it.

Get the Catatonia report as a PDF

The PDF carries up to 50 rows of each section, where the page shows the first few, with the sources listed. Enter a work email and confirm it from the message we send, and the report follows by email.

When did Catatonia trials start? (10)

Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.

Trials over time, by phase

  • Phase 1
  • Phase 2
  • Phase 4
  • Not applicable
  • Observational

Top of scale: 4

2004: 2 trials (Observational 1, Phase 2 1) 2006: 1 trials (Observational 1) 2013: 1 trials (Phase 1 1) 2017: 2 trials (Not applicable 2) 2020: 3 trials (Observational 3) 2021: 1 trials (Phase 4 1) 2023: 4 trials (Not applicable 2, Phase 2 1, Phase 1 1) 2024: 2 trials (Observational 1, Not applicable 1) 2025: 2 trials (Observational 1, Not applicable 1)

Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.

Trials started per year
Year Trials started
2026 (partial year) 4
2025 2
2024 2
2023 4
2021 1
2020 3
2017 2
2013 1
2006 1
2004 2

No forecast is made for this condition: it averages 2.0 trial starts a year over the five years to September, under the 5 a year the method needs.

Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.

What phase are Catatonia trials in? (5)

Shown in this order: phase order.

Show the trials by phase as a table
Trials by phase
Phase Trials
Phase 1 2
Phase 2 2
Phase 4 1
Not applicable 9
Observational 8

How many Catatonia trials are recruiting? (7)

Shown in this order: the order a trial moves through, from not yet recruiting to unknown.

Trials by recruitment status
Status Trials
Not yet recruiting 3
Recruiting 5
Active, not recruiting 1
Completed 7
Terminated 1

Status as registered on ClinicalTrials.gov. Each trial is counted once.

Which lead sponsors run the most Catatonia trials? (3)

Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.

Lead sponsors
Sponsor Trials
GlaxoSmithKline 1
Janssen, LP 1
Moscow Psychiatric Hospital No. 1 Named after N.A. Alexeev 1

Which drugs are being tested for Catatonia? (5)

Shown in this order: most trials first. One row per drug, matched to a single molecule under all its names, ranked by number of trials.

Drugs tested
Drug Trials
Lorazepam 2
Clonazepam 1
(CP-6890,550) Tofacitinib 1
Talnetant 1
Immunoglobulin 1

Interventions as named in the registry (5)

Shown in this order: most trials first.

Interventions as named in the registry
Drug Trials
Electroconvulsive Therapy 3
IR Risperidone 2
Blood sampling, lumbar puncture, stool sampling, skin microbiopsy and psychometrics scales 1
Intranasal Midazolam 1
Clonidin 1

These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.

Which publications cover Catatonia? (59)

Shown in this order: major-topic papers first, then newest, then most linked to trials.

Publications
Publication Journal Year Major topic
The Population-Based Incidence and Prevalence of Catatonia. The Journal of neuropsychiatry and clinical neurosciences 2025 Yes
Longitudinal Symptom Burden and Pharmacologic Management of Catatonia in Autism With Intellectual Disability: An Observational Study. Autism research : official journal of the International Society for Autism Research 2025 Yes
Genetics of catatonia: a systematic review of case reports and a gene pathway analysis. European psychiatry : the journal of the Association of European Psychiatrists 2025 Yes
Emergency Department Presentations for Catatonia: A 2019-2021 National Emergency Department Sample Study. Journal of the Academy of Consultation-Liaison Psychiatry 2025 Yes
Lorazepam in catatonia - Past, present and future of a clinical success story. Schizophrenia research 2024 Yes

Not on this page

Not measured: delivery record.

Checked, with nothing recorded for this condition: serious adverse events in this condition's trials, prevalence, rare-disease identity, and sub-conditions in mesh.

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