Condition (MeSH)
Cerebrospinal Fluid Otorrhea
ClinicalTrials.gov lists 15 trials for Cerebrospinal Fluid Otorrhea or a narrower condition beneath it. Ethicon, Inc. has the most among industry and government lead sponsors, with 3.
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Trials per phase
15 of the 15 trials are tagged with Cerebrospinal Fluid Otorrhea itself; the rest are tagged with a narrower condition beneath it.
When did Cerebrospinal Fluid Otorrhea trials start? (11)
Shown in this order: most recent first, 1990 onwards. 2026 is partial: trials registered with a 2026 start date so far, not a full year.
Trials over time, by phase
- Phase 2/3
- Phase 3
- Not applicable
- Observational
Top of scale: 3
Trials registered with a start date in each year, 1990 onward, stacked by phase (complete years only; the current partial year is in the table's notes). The table below lists the same counts, most recent years first.
| Year | Trials started |
|---|---|
| 2026 (partial year) | 1 |
| 2025 | 2 |
| 2024 | 3 |
| 2021 | 1 |
| 2020 | 2 |
| 2019 | 1 |
| 2015 | 1 |
| 2014 | 1 |
| 2011 | 1 |
| 2010 | 1 |
Showing 10 of 11 earlier years.
No forecast is made for this condition: it averages 1.2 trial starts a year over the five years to September, under the 5 a year the method needs.
Recruitment duration, a model prediction: 3 trials still running at the 2026-10-09 snapshot, fewer than the 5 needed for a median. Source: ClinicalTrials.gov / AACT (CTTI), public domain.
What phase are Cerebrospinal Fluid Otorrhea trials in? (4)
Shown in this order: phase order.
Show the trials by phase as a table
| Phase | Trials |
|---|---|
| Phase 2/3 | 1 |
| Phase 3 | 3 |
| Not applicable | 7 |
| Observational | 4 |
How many Cerebrospinal Fluid Otorrhea trials are recruiting? (5)
Shown in this order: the order a trial moves through, from not yet recruiting to unknown.
| Status | Trials |
|---|---|
| Recruiting | 5 |
| Enrolling by invitation | 1 |
| Completed | 6 |
| Terminated | 2 |
| Withdrawn | 1 |
Status as registered on ClinicalTrials.gov. Each trial is counted once.
Which lead sponsors run the most Cerebrospinal Fluid Otorrhea trials? (4)
Shown in this order: most trials first. Lead sponsors the registry classes as industry, NIH, US federal, other government or network. A hospital or university the registry files as government can appear here. Sponsors it classes as academic or other are shown on the full page, because that class cannot separate an institution from a named investigator.
| Sponsor | Trials |
|---|---|
| Ethicon, Inc. | 3 |
| Cook Research Incorporated | 1 |
| Medprin Regenerative Medical Technologies Co., Ltd. | 1 |
| Stryker Craniomaxillofacial | 1 |
Interventions as named in the registry (2)
Shown in this order: most trials first.
| Drug | Trials |
|---|---|
| EVICEL Fibrin Sealant | 2 |
| EVICEL | 1 |
These are the names sponsors entered on ClinicalTrials.gov that we have not matched to a single molecule. Some are drugs under a brand or code name; others are procedures, doses or arm labels.
Which serious adverse events do Cerebrospinal Fluid Otorrhea trials report? (10)
Shown in this order: most subjects affected first. Subjects affected summed across trials, a cross-trial signal, not a rate.
| Adverse event | Subjects affected | Trials |
|---|---|---|
| Pseudomeningocele | 16 | 2 |
| Convulsion | 7 | 2 |
| Pneumonia | 7 | 1 |
| Postoperative wound infection | 7 | 1 |
| Glioblastoma | 6 | 1 |
Showing 5 of 10 adverse events.
Which publications cover Cerebrospinal Fluid Otorrhea? (6)
Shown in this order: major-topic papers first, then newest, then most linked to trials.
| Publication | Journal | Year | Major topic |
|---|---|---|---|
| Ciprofloxacin/dexamethasone drops decrease the incidence of physician and patient outcomes of otorrhea after tube placement. | International journal of pediatric otorhinolaryngology | 2007 | Yes |
| Otorrhea after grommet insertion for middle ear effusion in patients with nasopharyngeal carcinoma. | American journal of otolaryngology | 1999 | Yes |
| Timing of antiretroviral therapy after diagnosis of cryptococcal meningitis. | The New England journal of medicine | 2014 | No |
| Comparison between myringotomy and tympanostomy tubes in combination with adenoidectomy in 3-7-year-old children with otitis media with effusion. | International journal of pediatric otorhinolaryngology | 2010 | No |
| Pituitary surgery: transsphenoidal approach. | Neurosurgery | 2002 | No |
Showing 5 of 6 publications.
Not on this page
Not measured: delivery record.
Checked, with nothing recorded for this condition: prevalence, rare-disease identity, and sub-conditions in mesh.